Risk Factors for Post-ERCP Cholangitis in Patients with Pancreatic Cancer from a Single Referral Center in Iran

Salehimarzijarani, Babak; Dadvar, Zohreh; Mousavi, Mirhadi; Mirsattari, Dariush; Zali, Mohammad Reza; Alizadeh, Amir Houshang Mohammad

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자료유형: 학술저널

저자정보: Salehimarzijarani, Babak (Taleghani Hospital, Shahid Beheshti University of Medical Sciences) Dadvar, Zohreh (Taleghani Hospital, Shahid Beheshti University of Medical Sciences) Mousavi, Mirhadi (Taleghani Hospital, Shahid Beheshti University of Medical Sciences) Mirsattari, Dariush (Taleghani Hospital, Shahid Beheshti University of Medical Sciences) Zali, Mohammad Reza (Taleghani Hospital, Shahid Beheshti University of Medical Sciences) Alizadeh, Amir Houshang Mohammad (Taleghani Hospital, Shahid Beheshti University of Medical Sciences)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제13권 제4호

발행연도: 2012.1

수록면: 1,539 - 1,541 (3page)

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Cholangitis is relatively uncommon but associated mortality is high due to the predisposition in people with underlying disease. For this recognition of contributing risk factors is necessary. Therefore, the present descriptive-analytical cross-sectional survey was designed to determine contributing risk factors for post-ERCP cholangitis in patients with pancreatic cancer. From 2005 to 2010, 110 consecutive cases of pancreatic cancer attending to a tertiary referral centre (Taleghani Hospital), Tehran, Iran were recruited. The patients all underwent stenting via endoscopic retrograde cholangiopancreatography (ERCP). On univariate analysis, a metallic stent type (95% confidence interval (CI) 1.025-11.34, P=0.037), having no jaundice (1.44-2.22, P=0.009), having no pain (1.32-1.91, P=0.026), a history of prior ERCP (1.16-10.37, P=0.020), and having a proximal biliary stone (1.002-5.93, P=0.046) were related to cholangitis. However on multivariate analysis, none of these factors were found to be contributing risk factors. Cholangitis is avoidable with adequate biliary drainage. Because success rates are higher and complication rates lower for endoscopists performing large volumes of ERCP, performance of the procedure should be concentrated as much as possible in institutions with endoscopists having adequate experience. Patients with a high risk for complications may be best served by referral to an advanced center.

#Therapeutic-ERCP #cholangitis #risk factors #referral center #Iran

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