Cancer Patients Are at High Risk of Mortality if Presenting with Sepsis at an Emergency Department

Prachanukool, Thidathit; Tangkulpanich, Panvilai; Paosaree, Possawee; Sawanyawisuth, Kittisak; Sitthichanbuncha, Yuwares

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자료유형: 학술저널

저자정보: Prachanukool, Thidathit (Department of Emergency Medicine, Faculty of Medicine, Ramathibodi Hospital Mahidol University) Tangkulpanich, Panvilai (Department of Emergency Medicine, Faculty of Medicine, Ramathibodi Hospital Mahidol University) Paosaree, Possawee (Department of Emergency Medicine, Faculty of Medicine, Ramathibodi Hospital Mahidol University) Sawanyawisuth, Kittisak (Department of Medicine, Faculty of Medicine, Khon Kaen University) Sitthichanbuncha, Yuwares (Department of Emergency Medicine, Faculty of Medicine, Ramathibodi Hospital Mahidol University)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제17권 제7호

발행연도: 2016.1

수록면: 3,423 - 3,426 (4page)

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Background: Sepsis is an emergency condition with high mortality and morbidity rate. There are limited data on the association of cancer as a risk factor for mortality in sepsis patients in the emergency department (ED). Materials and Methods: This retrospective study was conducted at the ED, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand. The study period was between January 1st and December $31^{st}$, 2014. The inclusion criteria were as follows: adult patients over 15 years of age who presented at the ED with suspicion of sepsis, received treatment at the ED, and whose blood culture was found to be positive. Clinical data were recorded from medical records including the Mortality in Emergency Department Sepsis score (MEDS score). The primary outcome of this study was mortality at one month. Multivariate logistic regression analysis was used to identify independent factors associated with death. Results: During the study period, there were 775 eligible patients. The two most common pathogens identified from blood cultures were Staphylococcus aureus (193 patients; 24.9%) and Escherichia coli (158 patients; 20.4%). At one month after presenting at the ED, 110 patients (14.2%) had died. There were four significant factors for death, having cancer, being on an endotracheal tube, initial diagnosis of bacteremia, and high MED scores. Having cancer had an adjusted OR of 2.12 (95% CI of 1.29, 3.47). Conclusions: Cancer patients have double the risk of mortality if presenting with sepsis at the ED.

#Sepsis #cancer #death #predictors #emergency department

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Prachanukool, Thidathit

소속기관 Department of Emergency Medicine, Faculty of Medicine, Ramathibodi Hospital Mahidol University