Clinical Effectiveness of Preoperative Embolization for Cerebellar Hemangioblastoma

Liu, Ai-Hua; Peng, Tang-Ming; Wu, Zhen; Xiao, Xin-Ru; Jiang, Chu-Han; Wu, Zhong-Xue; Li, You-Xiang

추천

검색

자료유형: 학술저널

저자정보: Liu, Ai-Hua (Department of Interventional Neuroradiology, Beijing Neurosurgical Institute) Peng, Tang-Ming (Department of Interventional Neuroradiology, Beijing Neurosurgical Institute) Wu, Zhen (Department of neurosurgery, Beijing Tiantan Hospital, Capital Medical University) Xiao, Xin-Ru (Department of neurosurgery, Beijing Tiantan Hospital, Capital Medical University) Jiang, Chu-Han (Department of Interventional Neuroradiology, Beijing Neurosurgical Institute) Wu, Zhong-Xue (Department of Interventional Neuroradiology, Beijing Neurosurgical Institute) Li, You-Xiang (Department of Interventional Neuroradiology, Beijing Neurosurgical Institute)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제14권 제9호

발행연도: 2013.1

수록면: 5,179 - 5,183 (5page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

The cerebellar hemangioblastoma (CHB) has an abundant blood supply and deep anatomical location. Complete surgical resection is generally very difficult. This study investigated the safety and effectiveness of preoperative embolization followed by surgical resection of CHB in a large cohort of patients. A database of 125 CHB patients with surgical resection in Beijing Tiantan Hospital between July 2006 and July 2012 was reviewed. Of those, 46 cases (experimental group) received preoperative embolization, 79 cases (control group) underwent surgery without embolization. Patient demographics, tumor size, duration of surgery, blood loss, blood transfusion, complications and follow-up results were collected and analyzed retrospectively. In the experimental group, the Kamofsky score (KS) was 80-100 in 40 cases (86.9%), 40-70 in 4 cases (8.7%), and below 40 in 2 cases (4.3%). Among 31 cases with follow-up, KS was 80-100 in 27 cases (87.1%), 40-70 in 2 cases (6.5%), and 0 in 2 cases (6.5%). In control group, KS was 80 -100 in 65 cases (82.2%), 40-70 in 6 cases (7.6%), 10-30 in 3 cases (3.8%), and 0 in 3 cases (3.8%). Among 53 cases with follow-up, KS was 80-100 in 44 cases (83.0%), 40-70 in 4 cases (7.5%), 10-30 in 1 case (1.9%), and 0 in 4 cases (7.5%). There were statistically significant differences between the experimental and control groups in tumor size, duration of surgery, amount of intraoperative blood loss and transfusion (p<0.01). However, complications (p=0.31) and follow-up results (p=0.76) showed no significant differences between groups. Selective preoperative embolization of those CHB patients with richer blood supply, higher hemorrhage risk, is safe and effective, and is a reliable adjuvant therapy for complete surgical resection of CHB.

#Hemangioblastoma #embolization #surgical resection

참고문헌 (0)

참고문헌 신청

참고문헌이 DBpia에서 서비스 중이라면, [참고문헌 신청]을 통해 등록해보세요