Four Year Trend of Carbapenem-Resistance in Newly Opened ICUs of a University-Affiliated Hospital of South Korea

Kim, Bo-Min; Jeon, Eun-Ju; Jang, Ju-Young; Chung, Jin-Won; Park, Ji-Hoon; Choi, Jae-Chol; Shin, Jong-Wook; Park, In-Won; Choi, Byoung-Whui; Kim, Jae-Yeol

추천

검색

자료유형: 학술저널

저자정보: Kim, Bo-Min (Division of Pulmonary and Allergy, Department of Internal Medicine, Chung-Ang University College of Medicine) Jeon, Eun-Ju (Division of Pulmonary and Allergy, Department of Internal Medicine, Chung-Ang University College of Medicine) Jang, Ju-Young (Division of Pulmonary and Allergy, Department of Internal Medicine, Chung-Ang University College of Medicine) Chung, Jin-Won (Division of Pulmonary and Allergy, Department of Internal Medicine, Chung-Ang University College of Medicine) Park, Ji-Hoon (Division of Pulmonary and Allergy, Department of Internal Medicine, Chung-Ang University College of Medicine) Choi, Jae-Chol (Division of Pulmonary and Allergy, Department of Internal Medicine, Chung-Ang University College of Medicine) Shin, Jong-Wook (Division of Pulmonary and Allergy, Department of Internal Medicine, Chung-Ang University College of Medicine) Park, In-Won (Division of Pulmonary and Allergy, Department of Internal Medicine, Chung-Ang University College of Medicine) Choi, Byoung-Whui (Division of Pulmonary and Allergy, Department of Internal Medicine, Chung-Ang University College of Medicine) Kim, Jae-Yeol (D)

저널정보: 대한결핵 및 호흡기학회 Tuberculosis and Respiratory Diseases 결핵 및 호흡기 질환 제72권 제4호

발행연도: 2012.1

수록면: 360 - 366 (7page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Background: Carbapenem-resistance is rapidly evolving among the pathogenic microbes in intensive care units (ICUs). This study aimed to determine annual trend of carbapenem-resistance in the ICU for 4 years, since the opening of a university-affiliated hospital in South Korea. Methods: From 2005 to 2008, microbial samples from consecutive 6,772 patients were screened in the ICU. Three hundred and ninety-seven patients (5.9%) and their first isolates of carbapenem-resistant pathogens were analyzed. Results: The percentage of patients infected with carbapenem-resistant organisms increased constantly during the initial three years (2.3% in 2005, 6.2% in 2006, 7.8% in 2007), then it declined to 6.5% in 2008. Acute Physiology and Chronic Health Evaluation (APACHE) III score at admission was $58.0{\pm}23.5$, the median length of the ICU stay was 37 days, and the mortality rate was 37.5%. The sampling sites were endotracheal suction (67%), catheterized urine (17%), wound (6%) and others (10%). Bacteria with carbapenem-resistance were Pseudomonas aeruginosa (247 isolates, 62%), Acinetobacter baumannii (117 isolates, 30%), Enterobacteriaceae (12 isolates, 3%), and others (21, 5%). Of note, peak isolation of carbapenem-resistant microorganisms in medical ICU was followed by the same epidemic at surgical ICU. Conclusion: Taken together, carbapenem-resistant pathogens are of growing concern in the ICU.

#Carbapenems #Drug Resistance, Bacterial #Intensive Care Units

참고문헌 (0)

참고문헌 신청

참고문헌이 DBpia에서 서비스 중이라면, [참고문헌 신청]을 통해 등록해보세요