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논문 기본 정보

자료유형
학술저널
저자정보
Ha, Eun Sil (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) Kim, Hye Ok (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) Lee, Kyoung Ju (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) Lee, Eun Joo (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) Hur, Gyu Young (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) Jung, Ki Hwan (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) Lee, Sung Yong (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) Kim, Je Hyeong (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) Lee, Sang Yeub (Division) Shin, Chol Shim, Jae Jeong Kang, Kyung Ho Yoo, Se Hwa In, Kwang Ho
저널정보
대한결핵 및 호흡기학회 Tuberculosis and Respiratory Diseases 결핵 및 호흡기 질환 제67권 제6호
발행연도
2009.1
수록면
506 - 511 (6page)

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Background: The smoking prevalence in asthma patients are similar to those in the general population. Asthma and active cigarette smoking can interact to create more severe symptoms, an accelerated decline in lung function and impaired therapeutic responses. Accordingly, asthmatics with a history of smoking were examined to define the clinical characteristics and lung function of smoking asthmatics. Methods: The medical records of 142 asthmatics with a known smoking history were reviewed. The patients were divided into three groups according to their smoking history - current smokers, former smokers and non-smokers. The clinical characteristics, lung function, and annual declines of the forced expiratory volume in one second ($FEV_1$) were compared. Results: Fifty-three of the 142 patients (37%) were current smokers, 24 were former smokers (17%) and 65 were non-smokers (45%). The patients with a hospital admission history during the previous year included 16 current smokers (30%), 4 former smokers (17%) and 7 non-smokers (11%) (p=0.02). The mean $FEV_1$ (% predicted) was 76.8${\pm}$19.8%, 71.6${\pm}$21.1% and 87.9${\pm}$18.7% for current smokers, former smokers and non-smokers, respectively (p< 0.001). The $FEV_1$/forced vital capacity (FVC) (ratio, %) values were 63.6${\pm}$12.6%, 59.3${\pm}$14.9% and 72.1${\pm}$11.8% in current smokers, former smokers and non-smokers, respectively (p<0.001). The corresponding mean values for the individual $FEV_1$ slopes were not significant (p=0.33). Conclusion: Asthmatic smokers demonstrated higher hospital admission rates and lower lung function. These findings suggest that the smoking history is an important predictor of a poor clinical outcome in asthma patients.

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