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자료유형
학술저널
저자정보
Kim, Hye-Jin (Department of Internal Medicine, Soonchunhyang University College of Medicine) Koo, So-My (Department of Internal Medicine, Soonchunhyang University College of Medicine) Ham, Nam-Suk (Department of Internal Medicine, Soonchunhyang University College of Medicine) Kim, Ki-Up (Department of Internal Medicine, Soonchunhyang University College of Medicine) Uh, Soo-Taek (Department of Internal Medicine, Soonchunhyang University College of Medicine) Kim, Yang-Ki (Department of Internal Medicine, Soonchunhyang University College of Medicine)
저널정보
대한결핵 및 호흡기학회 Tuberculosis and Respiratory Diseases 결핵 및 호흡기 질환 제76권 제3호
발행연도
2014.1
수록면
127 - 130 (4page)

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The risk of dying from a pulmonary embolism (PE) is estimated to be about 30% if inotropic support is required and no cardiopulmonary arrest occurs. Fibrinolysis in massive PE is regarded as a life-saving intervention, unless there is a high risk of bleeding following the use of the fibrinolytic therapy. Rivaroxaban is an oral factor Xa inhibitor, however its anticoagulation effects before or after administration of fibrinolytics in massive PE are still unknown. Two patents were admitted: 61-year-old woman with repeated syncope, and a 73-year-old woman was admitted with dyspnea and poor oral intake. Systemic arterial hypotension with radiologic confirmation led to a diagnosis of massive PE in both patients. Rivaroxaban was administered before in one, and after firbrinolytic therapy in the other. One showed similar efficacy of rivaroxaban with currently used anticoagulants after successful fibrinolysis, and the other one without antecedent administration of the fibrinolytic agent showed unfavorable efficacy of rivaroxaban.

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