Breastfeeding and its Relationship with Reduction of Breast Cancer: A Review

Franca-Botelho, Aline Do Carmo; Ferreira, Marina Carvalho; Franca, Juliana Luzia; Franca, Eduardo Luzia; Honorio-Franca, Adenilda Cristina

추천

검색

자료유형: 학술저널

저자정보: Franca-Botelho, Aline Do Carmo (Institute of Health Sciences, Centro Universitario do Planalto de Araxa) Ferreira, Marina Carvalho (Institute of Health Sciences, Centro Universitario do Planalto de Araxa) Franca, Juliana Luzia (Institute of Health Sciences, Centro Universitario do Planalto de Araxa) Franca, Eduardo Luzia (Institute of Biological and Health Science, Universidade Federal de Mato Grosso) Honorio-Franca, Adenilda Cristina (Institute of Biological and Health Science, Universidade Federal de Mato Grosso)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제13권 제11호

발행연도: 2012.1

수록면: 5,327 - 5,332 (6page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

In this review, we describe the patterns of known immunological components in breast milk and examine the relationship between breastfeeding and reduced risk of breast cancer. The top risk factors for breast cancer are a woman's age and family history, specifically having a first-degree relative with breast cancer. Women that have a history of breastfeeding have been shown to have reduced rates of breast cancer. Although the specific cause has not been elucidated, previous studies have suggested that breastfeeding reduces the risk of breast cancer primarily through two mechanisms: the differentiation of breast tissue and reduction in the lifetime number of ovulatory cycles. In this context, one of the primary components of human milk that is postulated to affect cancer risk is alpha-lactalbumin. Tumour cell death can be induced by HAMLET (a human milk complex of alpha-lactalbumin and oleic acid). HAMLET induces apoptosis only in tumour cells, while normal differentiated cells are resistant to its effects. Therefore, HAMLET may provide safe and effective protection against the development of breast cancer. Mothers should be encouraged to breastfeed their babies because the complex components of human milk secretion make it an ideal food source for babies and clinical evidence has shown that there is a lower risk of breast cancer in women who breastfed their babies.

#Breast cancer #breastfeeding #breast milk #alpha-lactalbumin

참고문헌 (0)

참고문헌 신청

참고문헌이 DBpia에서 서비스 중이라면, [참고문헌 신청]을 통해 등록해보세요