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논문 기본 정보

자료유형
학술저널
저자정보
Sun, Jia-Yang (Department of Thoracic Surgery, Beijing Chest Hospital, Capital Medical University) Shi, Lei (Department of Hepatobiliary Surgery, The First Affiliated Hospital, Xi'an Jiaotong University) Gao, Xu-Dong (Department of Thoracic Surgery, The Affiliated Hospital of Inner Mongolia Medical University) Xu, Shao-Fa (Department of Thoracic Surgery, Beijing Chest Hospital, Capital Medical University)
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제13권 제7호
발행연도
2012.1
수록면
3,143 - 3,147 (5page)

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Background: Previous studies investigating the association of physical activity with risk of lung cancer reported conflicting results. In order to update and improve available evidence on any link, a meta-analysis was performed. Method: We searched the PubMed database for prospective cohort studies investigating the relation of physical activity with risk of lung cancer. The pooled relative risk (RR) with its 95% confidence intervals (95%CI) was used to assess the association. Results: We included 14 prospective studies with a total of 1,644,305 participants, with 14,074 incident lung cancer cases documented during follow-up. Meta-analysis of all 14 studies suggested both high and medium levels of physical activity to be associated with decreased risk of lung cancer compared to the reference group with low level of physical activity (for high level, RR = 0.77, 95%CI 0.73-0.81, P < 0.001; for medium level, RR = 0.87, 95%CI 0.83-0.90, P < 0.001). Subgroup analyses by gender found obvious associations in both men and women. No publication bias was observed. Conclusion: Our findings suggest that high and medium levels of physical activity have a beneficial effect on lung cancer by reducing the overall risk of tumour development among both men and women.

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