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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 306 - 311 (6page)
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초록· 키워드
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Stevioside, a natural sweeteners presently used in various kinds of food and food products in Korea, was evaluated for its toxicity potential in the 14 day feeding study using B6C3F1 mice. Stevioside was added to the diet at different concentrations of 0.31, 0.62, 1.25, 2.5 and 5%, and was administered for 14 consecutive days. An increase of liver organ weight in male mice was observed. No diet-related differences were noted in clinical signs, food consumption, and gross and histopatholgical evaluation. Based on these results, we concluded that the concentration of 5% in the diet was a suitable maximum tolerable dose of stevioside for a 90 day study in mice.
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참고문헌 (27)
참고문헌 신청
Forshee, R.A / 2003 / Total beverage consumption and beverage choices among children and adolescents / Int. J. Food Sci. Nutr 87:287~291
World Health Organization / 2005 / JECFA Steviol glycosides, in 63rd Meeting of the Joint FAO/ WHO Expert Committee on Food Additives :34
Lee, B.M / 1996 / Stevioside, a natural sweetner: Is it safe? / J. Fd. Hyg. Safety 11(4):323~327
Choi, D.W / 2002 / Regulation and quality control of herbal drugs in korea / Toxicology 181
Compadre, C.M / 1988 / Mass spectral analysis of some derivatives and in vitro metabolites of steviol, the aglycone of the natural sweetners, stevioside, rebaudioside A, and rubusoside / Biomed. Environ. Mass spectrum 15(4):211~222
World Health Organization / 2005 / JECFA Steviol glycosides, in 63rd Meeting of the Joint FAO/ WHO Expert Committee on Food Additives :34
Lee, B.M / 1996 / Stevioside, a natural sweetner: Is it safe? / J. Fd. Hyg. Safety 11(4):323~327
Choi, D.W / 2002 / Regulation and quality control of herbal drugs in korea / Toxicology 181
Compadre, C.M / 1988 / Mass spectral analysis of some derivatives and in vitro metabolites of steviol, the aglycone of the natural sweetners, stevioside, rebaudioside A, and rubusoside / Biomed. Environ. Mass spectrum 15(4):211~222
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