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논문 기본 정보

자료유형
학술저널
저자정보
Sung, Won-Mo (Interdisciplinary Program in Radiation Applied Life Science, Seoul National University College of Medicine) Park, Jong-Min (Interdisciplinary Program in Radiation Applied Life Science, Seoul National University College of Medicine) Choi, Chang-Heon (Interdisciplinary Program in Radiation Applied Life Science, Seoul National University College of Medicine) Ha, Sung-Whan (Interdisciplinary Program in Radiation Applied Life Science, Seoul National University College of Medicine) Ye, Sung-Joon (Interdisciplinary Program in Radiation Applied Life Science, Seoul National University College of Medicine)
저널정보
대한방사선종양학회 Radiation oncology journal : ROJ Radiation oncology journal : ROJ 제30권 제1호
발행연도
2012.1
수록면
27 - 35 (9page)

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Purpose: To evaluate the effect of common three photon energies (6-MV, 10-MV, and 15-MV) on intensity-modulated radiation therapy (IMRT) plans to treat prostate cancer patients. Materials and Methods: Twenty patients with prostate cancer treated locally to 81.0 Gy were retrospectively studied. 6-MV, 10-MV, and 15-MV IMRT plans for each patient were generated using suitable planning objectives, dose constraints, and 8-field setting. The plans were analyzed in terms of dose-volume histogram for the target coverage, dose conformity, organs at risk (OAR) sparing, and normal tissue integral dose. Results: Regardless of the energies chosen at the plans, the target coverage, conformity, and homogeneity of the plans were similar. However, there was a significant dose increase in rectal wall and femoral heads for 6-MV compared to those for 10-MV and 15-MV. The $V_{20Gy}$ of rectal wall with 6-MV, 10-MV, and 15-MV were 95.6%, 88.4%, and 89.4% while the mean dose to femoral heads were 31.7, 25.9, and 26.3 Gy, respectively. Integral doses to the normal tissues in higher energy (10-MV and 15-MV) plans were reduced by about 7%. Overall, integral doses in mid and low dose regions in 6-MV plans were increased by up to 13%. Conclusion: In this study, 10-MV prostate IMRT plans showed better OAR sparing and less integral doses than the 6-MV. The biological and clinical significance of this finding remains to be determined afterward, considering neutron dose contribution.

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