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학술저널
저자정보
Kim, Ji Hye (Department of Pediatrics, Seoul National University Children's Hospital, Seoul National University College of Medicine) Kim, Ji Hyun (Department of Pediatrics, Seoul National University Children's Hospital, Seoul National University College of Medicine) Cho, Myung Hyun (Department of Pediatrics, Korea Cancer Center Hospital) Park, Eujin (Department of Pediatrics, Hallym University Kangnam Sacred Heart Hospital) Hyun, Hye Sun (Department of Pediatrics, St. Vincent's Hospital, The Catholic University of Korea) Ahn, Yo Han (Department of Pediatrics, Seoul National University Bundang Hospital) Kang, Hee Gyung (Department of Pediatrics, Seoul National University Children's Hospital, Seoul National University College of Medicine) Moon, Kyung Chul (Department of Pathology, Seoul National University Hospital) Ha, Il-Soo (Department of Pediatrics, Seoul National University Children's Hospital, Seoul National University College of Medicine) Cheong, Hae Il (Department of Pediatrics, Seoul National University Children's Hospital, Seoul National University College of Medicine)
저널정보
대한소아청소년과학회 Clinical and Experimental Pediatrics Korean journal of pediatrics 제62권 제4호
발행연도
2019.1
수록면
144 - 147 (4page)

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The most common type of refractory hypertension found in children is secondary hypertension, which is a potentially curable disease. Reninoma, a renin-secreting juxtaglomerular cell tumor, is a rare cause of severe hypertension that is usually diagnosed in adolescents and young adults. Surgical resection of the tumor completely cures the hypertension of patients with reninoma. The typical clinical presentation of reninoma includes hypokalemia, metabolic alkalosis, and features secondary to the increased activation of the renin-angiotensin system without renal artery stenosis. We report a case of reninoma in a female adolescent with a typical clinical presentation, in which surgical removal of the tumor completely cured hypertension. We discuss here the clinical features, imaging studies, and immunohistochemical examination of the tumor used to establish the diagnosis of reninoma and for the management of the condition.

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