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자료유형
학술저널
저자정보
Yoon, Ji-Eun (Department of Pediatrics, Chungbuk National University College of Medicine) Kim, Wun-Kon (Department of Pediatrics, Chungbuk National University College of Medicine) Lee, Jin-Seok (Laboratory Medicine, Chungbuk National University College of Medicine) Shin, Kyeong-Seob (Department of Pediatrics, Chungbuk National University College of Medicine) Ha, Tae-Sun (Department of Pediatrics, Chungbuk National University College of Medicine)
저널정보
대한소아청소년과학회 Clinical and Experimental Pediatrics Korean journal of pediatrics 제54권 제2호
발행연도
2011.1
수록면
79 - 85 (7page)

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Purpose: We studied the differences in the antibiotic susceptibilities of the microorganisms that causeing urinary tract infections (UTI) in children to obtain useful information on appropriate drug selection for childhood UTI. Methods: We retrospectively analyzed the antibiotic susceptibilities of 429 microorganisms isolated from 900 patients diagnosed with UTI in the Department of Pediatrics, Chungbuk National University Hospital, from 2003 to 2008. Results: The most common causative microorganisms for UTI were Escherichia coli (81.4%), Klebsiella pneumoniae (8.4%), Enterobacter spp. (1.7%), and Proteus spp. (0.4%). E. coli showed relatively high susceptibility as compared to imipenem (100%), amikacin (97.7%), aztreonam (97.9%), cefepime (97.7%), and ceftriaxone (97.1%), while it showed relatively low susceptibility to gentamicin (GM) (79.0%), trimethoprim/sulfamethoxazole (TMP/SMX) (68.7%), ampicillin/sulbactam (33.0%), and ampicillin (AMP) (28.6%). There were no significant differences in the image findings for causative microorganisms. Conclusion: Gram-negative organisms showed high susceptibility to amikacin and third-generation cephalosporins, and low susceptibility to AMP, GM, and TMP/SMX. Therefore, the use of AMP or TMP/SMX as the first choice in empirical and prophylactic treatment of childhood UTI in Korea should be reconsidered and investigated further.

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