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논문 기본 정보

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학술저널
저자정보
Kim, Ju Yeong (Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital) Yi, Gwang (Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital) Kim, Yeo Rang (Department of Obstetrics and Gynecology, Seoul National University Hospital) Chung, Jae Yeon (Department of Obstetrics and Gynecology, Seoul National University Hospital) Ahn, Ji Hyun (Department of Obstetrics and Gynecology, Seoul National University Hospital) Uhm, You Kyoung (Department of Obstetrics and Gynecology, Seoul National University Hospital) Jee, Byung Chul (Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital) Suh, Chang Suk (Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital) Kim, Seok Hyun (Department of Obstetrics and Gynecology, Seoul National University Hospital)
저널정보
대한생식의학회 Clinical and experimental reproductive medicine : CERM Clinical and experimental reproductive medicine : CERM 제40권 제2호
발행연도
2013.1
수록면
95 - 99 (5page)

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Objective: To evaluate the correlation between serum levels of anti-M$\ddot{u}$llerian hormone (AMH) and ovarian response to mild stimulation in normoovulatory women and anovulatory women with polycystic ovary syndrome (PCOS). Methods: Seventy-four cycles of mild stimulation (clomiphene citrate+gonadotropin followed by timed intercourse or intrauterine insemination) performed in normoovulatory women (57 cycles) and anovulatory women with PCOS (17 cycles). Ovarian sensitivity was defined by the number of mature follicles (${\geq}14mm$) on triggering day per 100 IU of gonadotropin. A correlation between ovarian sensitivity and the baseline serum AMH level (absolute or multiples of the median [MoM] value for each corresponding age) was calculated. Correlation between ovarian response and serum AMH level was evaluated. Results: Ovarian sensitivity to mild stimulation was positively correlated with absolute serum AMH (r=0.535, p<0.001) or AMH-MoM value (r=0.390, p=0.003) in normoovulatory women, but this correlation was not observed in anovulatory women with PCOS (r=0.105, p>0.05, r=-0.265, p>0.05, respectively). Conclusion: Ovarian response to mild stimulation is possibly predicted by the serum AMH level in normoovulatory women, but not in anovulatory women with PCOS.

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