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논문 기본 정보

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학술저널
저자정보
Han, Ae Ra (Department of Obstetrics and Gynecology, Kyungpook National University Hospital) Park, Chan Woo (Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Med) Lee, Hyoung-Song (Laboratory of Reproductive Biology and Infertility, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine) Yang, Kwang Moon (Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of M) Song, In Ok (Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medici) Koong, Mi Kyoung (Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of M)
저널정보
대한생식의학회 Clinical and experimental reproductive medicine : CERM Clinical and experimental reproductive medicine : CERM 제39권 제3호
발행연도
2012.1
수록면
114 - 117 (4page)

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Objective: It is well known that fresh blastocyst transfer results in better pregnancy outcomes with a smaller number of transferred embryos compared with cleavage stage embryo transfer. However, in terms of frozen-thawed blastocyst transfer, only a few studies are available. We aimed to evaluate clinical outcomes of frozen-thawed embryo transfer (FET) with blastocysts. Methods: Retrospective analysis of FET cycles with blastocysts (B-FET) between Jan 2007 and June 2009 was performed. Age-matched FET cycles with cleavage stage embryos (C-FET) during the same period were collected as controls. A total of 58 B-FET cycles were compared with 172 C-FET cycles and also compared with those of post-thaw extended culture blastocysts from frozen pronuclear stage embryos (22 cycles). Results: There was no difference in the patient characteristics of each group. The embryos' survival rates after thawing were comparable (>90%) and there was no difference in the implantation rate or clinical and ongoing pregnancy rate among the three groups. Conclusion: In FET, blastocyst transfers may not present better pregnancy outcomes than cleavage stage embryo transfers. A further large-scale prospective study is needed.
#Frozen-thawed embryo transfer #Blastocyst #Pregnancy outcome

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참고문헌 (15)

참고문헌 신청
Papanikolaou EG / 2008 / Live birth rates after transfer of equal number of blastocysts or cleavage-stage embryos in IVF. A systematic review and meta-analysis / Hum Reprod 23:91~99 google schola Papanikolaou EG / 2006 / In vitro fertilization with single blastocyst-stage versus single cleavage-stage embryos / N Engl J Med 354:1139~1146 google schola Blake DA / 2007 / Cleavage stage versus blastocyst stage embryo transfer in assisted conception / Cochrane Database Syst Rev 5 google schola Trounson A / 1983 / Human pregnancy following cryopreservation, thawing and transfer of an eight-cell embryo / Nature 305:707~709 google schola Liebermann J / 2003 / Recent developments in human oocyte, embryo and blastocyst vitrification: where are we now? / Reprod Biomed Online 7:623~633 google schola

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