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논문 기본 정보

자료유형
학술저널
저자정보
Kim, Jin Ju (Department of Obstetrics and Gynecology, Healthcare System Gangnam Center, Seoul National University Hospital) Choi, Young Min (The Institute of Reproductive Medicine and Population, Medical Research Center, Seoul National University College of Medicine) Chae, Soo Jin (Department of Obstetrics and Gynecology, Maria Fertility Hospital) Hwang, Kyu Ri (Department of Obstetrics and Gynecology, Seoul National University College of Medicine) Yoon, Sang Ho (Department of Obstetrics and Gynecology, Graduate School of Medicine, Dongguk University) Kim, Min Jeong (Department of Obstetrics and Gynecology, Healthcare System Gangnam Center, Seoul National University Hospital) Kim, Sun Mie (Department of Obstetrics and Gynecology, Healthcare System Gangnam Center, Seoul National University Hospital) Ku, Seung Yup (The Institute of Reproductive Medicine and Population, Medical Research Center, Seoul National University College of Medicine) Kim, Seok Hyun (The Institute of Reproductive Medicine and Population, Medical Research Center, Seoul National University College of Medicine) Kim, Jung Gu (Department of Obstetrics and Gyn)
저널정보
대한생식의학회 Clinical and experimental reproductive medicine : CERM Clinical and experimental reproductive medicine : CERM 제41권 제2호
발행연도
2014.1
수록면
80 - 85 (6page)

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Objective: To investigate: the prevalence of vitamin D deficiency in Korean women with polycystic ovary syndrome (PCOS), and the relationship between vitamin D status and clinical or metabolic features in this group. Methods: We recruited 38 women with PCOS using the Rotterdam criteria. A total of 109 premenopausal control women were matched with patients based on age and body mass index. Serum 25-hydroxy vitamin D concentrations less than 20 ng/mL were classified as frank vitamin D deficiency. Since vitamin D may play a significant role in metabolic disturbances in women with PCOS, correlations between clinical or metabolic parameters and vitamin D status were analyzed separately in patients and controls. Results: Women with PCOS showed no differences in the level of 25-hydroxy vitamin D ($19.6{\pm}6.6ng/mL$ in patients vs. $20.1{\pm}7.4ng/mL$ in controls, respectively, p=0.696) or prevalence of vitamin D deficiency (57.9% in patients vs. 56.5% in controls, respectively, p=0.880). In addition, we did not find any correlations between serum vitamin D level and clinical or metabolic profiles in either PCOS patients or controls. Conclusion: Our study found no differences in the absolute level of serum vitamin D between PCOS patients and matched controls. Prevalence of vitamin D deficiency was equally common among both patients and controls. Additionally, we did not find any correlations between serum vitamin D level and clinical or metabolic profiles, suggesting that the role of vitamin D in the pathogenesis of PCOS is not yet clear.

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