지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 105 - 112 (8page)
이용수
초록· 키워드
오류제보하기
In this study, the effects of iron on cytochrome c oxidase (CcO) in rat lung mitochondria were examined. Similar to liver mitochondria, iron accumulated considerably in lung mitochondria (more than 2-fold). Likewise, the reactive oxygen species and nitric oxide (NO) content of mitochondria were increased by more than 50% and 100%, respectively. NO might be produced by nitric oxide synthase (NOS), eNOS and iNOS type, with particular contribution by NOS in mitochondria. The respiratory control ratio of iron overloaded lung mitochondria dropped to nearly 50% due to increased state 4. Likewise, cytochrome c oxidase activity was lowered significantly to approximately 50% due to excess iron. Real-time PCR revealed that the expression of isoforms 1 and 2 of subunit IV of CeO was enhanced greatly under excess iron conditions. Taken together, these results show that oxidative phosphorylation within lung mitochondria may be influenced by iron overload through changes in cytochrome c oxidase and NO.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Iron Toxicity to Peritoneal Macrophage Due to Alteration of Mitochondria by NO
Korean journal of biological sciences
2004 .01
-
우(牛)심근조직의 mitochondria에서 cytochrome-c-oxidase의 형성과 변화
한국현미경학회지
2008 .01
-
Temporal changes in mitochondrial activities of rat heart after a single injection of iron, including increased complex II activity
Animal cells and systems
2010 .01
-
A Novel Protein in Mitochondria Interacts with Death Domain of Fadd and Induces Mitochondria-Mediated Cell Death
한국동물학회 학술대회
2001 .01
-
임신 쥐의 철 과잉섭취가 조직의 산화적 스트레스에 미치는 영향
한국영양학회지
2011 .02
-
Redox Regulation of Apoptosis before and after Cytochrome C Release
Korean journal of biological sciences
2003 .01
-
Trimorphomyces papilionaceus 미토콘드리아의 Cytochrome Oxidase Subunit Ⅱ 유전자의 부분적인 염기서열 분석
미생물학회지
1993 .10
-
Sequence Analysis of the Cytochrome b Gene of Trimorphomyces papilionaceus Mitochondria
The Journal of Microbiology
1995 .03
-
Clinical Study on the Iron Absorption from Heme-Iron Polypeptide and Nonheme-Iron
Nutritional Sciences
2006 .11
-
High Performance Magnetic Materials based on Metastable Iron / Iron Oxides
한국자기학회 학술연구발표회 논문개요집
2019 .05
-
누에의 말피기씨관에 대한 미세구조
한국곤충학회지
1982 .01
-
POSSIBLE INVOLVEMENT OF Fe-S CENTERS AS MAJOR ENDOGENOUS PHOTOSENSITIZERS IN HIGH LIGHT-CAUSED LOSS OF MEMBRANE STRUCTURE AND FUNCTION OF MITOCHONDRIA
Journal of photoscience : an international journal officail organ of the korean society of photoscience
1994 .01
-
Morphological Diversity of Mitochondria in Cultured Astrocyte, HeLa, COS7 Cells under High Voltage Electron Microscopy
한국현미경학회지
2013 .01
-
Mitochondria Cytochrome b Gene을 이용한 왜가리과 (Family Ardeidae)의 분자계통학적 분석
한국동물학회 학술대회
2003 .01
-
Effects of developmental iron deficiency and post-weaning iron repletion on the levels of iron transporter proteins in rats
Nutrition Research and Practice
2015 .12
-
Effects of developmental iron deficiency and post-weaning iron repletion on the levels of iron transporter proteins in rats
Nutrition Research and Practice
2015 .12
-
Effects of ATP and ADP on iron uptake in rat heart mitochondria
Animal cells and systems
2010 .01
-
임신기간 중 모체의 식사 철 섭취상태와 생체이용률 및 철 영양상태의 변화
대한지역사회영양학회지
2004 .04
-
Evidence for the Association of Ce11u1ar Iron Loss in Nitric Oxide-induced Apoptosis of HL-60 Cells: Involvement of p38 Kinase, c-Jun N-terminal Kinase, Cytochrome C Release, and Caspases Pathways
Korean journal of biological sciences
2002 .01
-
Cross-Sectional Study on Iron Status of Asan Residents and Regional Comparison
Journal of Community Nutrition
2003 .03
이 논문의 저자 정보
최근 본 자료
댓글(0)
0