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논문 기본 정보

자료유형
학술저널
저자정보
Yi, Young-Joo (Division of Biotechnology, College of Environmental& Bioresource Sciences, Chonbuk National University) Lee, In-Kyoung (Advanced Institute of Environment and Bioscience, Chonbuk National University) Seo, Dong-Won (Division of Biotechnology, College of Environmental& Bioresource Sciences, Chonbuk National University) Yun, Bong-Sik (Division of Biotechnology, College of Environmental& Bioresource Sciences, Chonbuk National University) Lee, Sang-Myeong (Division of Biotechnology, College of Environmental& Bioresource Sciences, Chonbuk National University)
저널정보
한국균학회 한국균학회지 한국균학회지 제44권 제2호
발행연도
2016.1
수록면
122 - 125 (4page)

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Phelligridin D (Phe D) is a compound isolated from Phellinus baumii, which is known for various biological activities. In this study, the authors examined the effect of Phe D on boar spermatozoa for its potential application in assisted reproductive technology for mammals. Sperm motility and deubiquitinylating activity significantly decreased when boar spermatozoa were incubated with Phe D (>$0.5{\mu}M$). The fluorescence intensities of dead sperm, and reactive oxygen species production increased after sperm incubation in the presence of Phe D. Although Phe D is associated with antioxidant and free radical scavenging activity, sperm viability deteriorated after its addition. This could lead to fertilization failure, including that following artificial insemination or in vitro fertilization. Phe D might have other biological functions in spermatozoa, and therefore requires additional studies in the future.

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