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논문 기본 정보

자료유형
학술저널
저자정보
Han, Ju-Hee (Department of Neurosurgery, Chonbuk National University Hospital and Medical School) Lee, Jong-Myong (Department of Neurosurgery, Chonbuk National University Hospital and Medical School) Koh, Eun-Jeong (Department of Neurosurgery, Chonbuk National University Hospital and Medical School) Choi, Ha-Young (Department of Neurosurgery, Chonbuk National University Hospital and Medical School)
저널정보
대한신경외과학회 대한신경외과학회지 대한신경외과학회지 제56권 제4호
발행연도
2014.1
수록면
303 - 309 (7page)

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Objective : The purpose of this study was to retrospectively review cases of intracerebral hemorrhage (ICH) medically treated at our institution to determine if the CT angiography (CTA) 'spot sign' predicts in-hospital mortality and clinical outcome at 3 months in patients with spontaneous ICH. Methods : We conducted a retrospective review of all consecutive patients who were admitted to the department of neurosurgery. Clinical data of patients with ICH were collected by 2 neurosurgeons blinded to the radiological data and at the 90-day follow-up. Results : Multivariate logistic regression analysis identified predictors of poor outcome; we found that hematoma location, spot sign, and intraventricular hemorrhage were independent predictors of poor outcome. In-hospital mortality was 57.4% (35 of 61) in the CTA spot-sign positive group versus 7.9% (10 of 126) in the CTA spot-sign negative group. In multivariate logistic analysis, we found that presence of spot sign and presence of volume expansion were independent predictors for the in-hospital mortality of ICH. Conclusion : The spot sign is a strong independent predictor of hematoma expansion, mortality, and poor clinical outcome in primary ICH. In this study, we emphasized the importance of hematoma expansion as a therapeutic target in both clinical practice and research.

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