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자료유형
학술저널
저자정보
Ruggeri, Andrea Gennaro (Department of Neurological Sciences-Neurosurgery, Sapienza University of Rome) Donnarumma, Pasquale (Department of Neurological Sciences-Neurosurgery, Sapienza University of Rome) Pichierri, Angelo (Department of Neurological Sciences-Neurosurgery, Sapienza University of Rome) Delfini, Roberto (Department of Neurological Sciences-Neurosurgery, Sapienza University of Rome)
저널정보
대한신경외과학회 대한신경외과학회지 대한신경외과학회지 제55권 제1호
발행연도
2014.1
수록면
40 - 42 (3page)

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A correlation between radiation therapy and cavernoma has been suspected since 1994. Since then, only a few cases of radio-induced cavernomas have been reported in the literature (85 patients). Most of them were children, and the most frequent original tumour had been medulloblastoma. The authors report a case of two cystic cavernous angiomas after radiation therapy for atypical meningioma in adult woman. This is the first case of cavernous angioma after radiotherapy for low grade meningioma. A 39-year-old, Latin american woman was operated on for a frontal atypical meningioma with intradiploic component and adjuvant radiotherapy was delivered (6000 cGy local brain irradiation, fractionated over 6 weeks). Follow-up MR imaging showed no recurrences of the tumour and no other lesions. Ten years later, at the age of 49, she consulted for progressive drug-resistant headache. MR imaging revealed two new well defined areas of different signal intensity at the surface of each frontal pole. Both lesions were surgically removed; the histopathological diagnosis was cavernous angioma. This is the first case of cavernous angioma after radiation therapy for atypical meningioma : it confirms the development of these lesions after standard radiation therapy also in patients previously affected by non-malignant tumours.

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