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논문 기본 정보

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학술저널
저자정보
Park, Sung Bae (Department of Neurosurgery, Seoul National University Boramae Medical Center) Chung, Chun Kee (Department of Neurosurgery, Seoul National University College of Medicine) Lee, Sang Hyung (Department of Neurosurgery, Seoul National University Boramae Medical Center) Yang, Hee-Jin (Department of Neurosurgery, Seoul National University Boramae Medical Center) Son, Young-Je (Department of Neurosurgery, Seoul National University Boramae Medical Center) Chung, Young Seob (Department of Neurosurgery, Seoul National University Boramae Medical Center)
저널정보
대한신경외과학회 대한신경외과학회지 대한신경외과학회지 제54권 제6호
발행연도
2013.1
수록면
496 - 500 (5page)

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Objective : To evaluate the successful fusion rate in postmenopausal women with single-level anterior cervical discectomy and successful fusion (ACDF) and identify the significant factors related to bone successful fusion in pre- and postmenopausal women. Methods : From July 2004 to December 2010, 108 consecutive patients who underwent single-level ACDF were prospectively selected as candidates. Among these, the charts and radiological data of 39 women were reviewed retrospectively. These 39 women were divided into two groups : a premenopausal group (n=11) and a postmenopausal group (n=28). To evaluate the significant factors affecting the successful fusion rate, the following were analyzed : the presence of successful fusion, successful fusion type, age, operated level, bone mineral density, graft materials, stand-alone cage or plating with autologous iliac bone, subsidence, adjacent segment degeneration, smoking, diabetes mellitus, and renal disease. Results : The successful fusion rates of the pre- and postmenopausal groups were 90.9% and 89.2%, respectively. There was no significant difference in the successful fusion rate or successful fusion type between the two groups. In the postmenopausal group, three patients (10.8%) had successful fusion failure. In the postmenopausal group, age and subsidence significantly affected the successful fusion rate (p=0.016 and 0.011, respectively), and the incidence of subsidence in patients with a cage was higher than that in patients with a plate (p=0.030). Conclusion : Menopausal status did not significantly affect bone successful fusion in patients with single-level ACDF. However, in older women with single-level ACDF, the combination of use of a cage and subsidence may unfavorably affect successful fusion.
#Menopause #Cervical #Discectomy #Successful fusion #Bone mineral density

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참고문헌 (22)

참고문헌 신청
Cavagna R / 2008 / Lumbar decompression and fusion in elderly osteoporotic patients : a prospective study using less rigid titanium rod fixation / J Spinal Disord Tech 21:86~91 google schola Chin DK / 2007 / Prevalence of osteoporosis in patients requiring spine surgery : incidence and significance of osteoporosis in spine disease / Osteoporos Int 18:1219~1224 google schola Ferguson SJ / 2002 / Anterior fixation in the osteoporotic spine : cut-out and pullout characteristics of implants / Eur Spine J 11:527~534 google schola Gercek E / 2003 / Subsidence of stand-alone cervical cages in anterior interbody fusion : warning / Eur Spine J 12:513~516 google schola Hadji P / 2012 / The impact of menopause on bone, zoledronic acid, and implications for breast cancer growth and metastasis / Ann Oncol 23:2782~2790 google schola

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