지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Objective : Sudden major cerebral artery occlusion often resists recanalization with currently available techniques or can results in massive symptomatic intracranial hemorrhage (sICH) after thrombolytic therapy. The purpose of this study was to examine mechanical recanalization with a retrievable self-expanding stent and balloon in acute intracranial artery occlusions. Methods : Twenty-eight consecutive patients with acute intracranial artery occlusions were treated with a Solitaire retrievable stent. Balloon angioplasty was added if successful recanalization was not achieved after stent retrieval. The angiographic outcome was assessed by Thrombolysis in Cerebral Infarction (TICI) and the clinical outcomes were assessed by the National Institutes of Health Stroke Scale (NIHSS) and the modified Rankin Scale (mRS). Results : At baseline, mean age was 69.4 years and mean initial NIHSS score was 12.5. A recanalization to TICI 2 or 3 was achieved in 24 patients (85%) after stent retrieval. Successful recanalization was achieved after additional balloon angioplasty in 4 patients. At 90-day follow-up, 24 patients (85%) had a NIHSS improvement of ${\geq}4$ and 17 patients (60%) had a good outcome (mRS ${\leq}2$). Although there was sICH, there was one death associated with the procedure. Conclusion : Mechanical thromboembolectomy with a retrievable stent followed by additional balloon angioplasty is a safe and effective first-line therapy for acute intracranial artery occlusions especially in case of unsuccessful recanalization after stent thrombectomy.
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참고문헌 (29)
참고문헌 신청
Arnold M / 2003 / Intra-arterial thrombolysis in 24 consecutive patients with internal carotid artery T occlusions / J Neurol Neurosurg Psychiatry 74:739~742
Bose A / 2008 / The Penumbra System : a mechanical device for the treatment of acute stroke due to thromboembolism / AJNR Am J Neuroradiol 29:1409~1413
Brekenfeld C / 2007 / Symptomatic intracranial haemorrhage after intra-arterial thrombolysis in acute ischaemic stroke : assessment of 294 patients treated with urokinase / J Neurol Neurosurg Psychiatry 78:280~285
Broderick JP / 2000 / Finding the most powerful measures of the effectiveness of tissue plasminogen activator in the NINDS tPA stroke trial / Stroke 31:2335~2341
Castaño C / 2010 / Mechanical thrombectomy with the Solitaire AB device in large artery occlusions of the anterior circulation : a pilot study / Stroke 41:1836~1840
Bose A / 2008 / The Penumbra System : a mechanical device for the treatment of acute stroke due to thromboembolism / AJNR Am J Neuroradiol 29:1409~1413
Brekenfeld C / 2007 / Symptomatic intracranial haemorrhage after intra-arterial thrombolysis in acute ischaemic stroke : assessment of 294 patients treated with urokinase / J Neurol Neurosurg Psychiatry 78:280~285
Broderick JP / 2000 / Finding the most powerful measures of the effectiveness of tissue plasminogen activator in the NINDS tPA stroke trial / Stroke 31:2335~2341
Castaño C / 2010 / Mechanical thrombectomy with the Solitaire AB device in large artery occlusions of the anterior circulation : a pilot study / Stroke 41:1836~1840
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