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학제간연구 과학기술학 뇌인지과학 기술정책 기타 복합학

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논문 기본 정보

자료유형
학술저널
저자정보
Lee, Hyun-Goo (Department of Neurosurgery, Bundang Jesaeng General Hospital) Rhim, Jong-Kook (Department of Neurosurgery, Bundang Jesaeng General Hospital) Kim, Yoon-Hee (Department of Neuroradiology, Bundang Jesaeng General Hospital) Sheen, Seung-Hun (Department of Neurosurgery, Hallym University College of Medicine) Oh, Sung-Han (Department of Neurosurgery, Bundang Jesaeng General Hospital) Chung, Bong-Sub (Department of Neurosurgery, Bundang Jesaeng General Hospital)
저널정보
대한신경외과학회 대한신경외과학회지 대한신경외과학회지 제50권 제4호
발행연도
2011.1
수록면
311 - 316 (6page)

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Objective : Stroke is the third leading cause of death in the Republic of Korea. Time is the most important factor in hyperacute stroke. Yet, there had been no protocol for mechanical thrombolysis. We have treated patients with hyperacute stroke by mechanical thrombolysis for 3 years. In current study, we analyzed the outcome of mechanical thrombolysis. Methods : From March 2008 to February 2011, 36 patients were treated with mechanical thrombolysis. Initially we treated the patients by aggressive mechanical clot disruption (AMCD) who were admitted within 6 hours after the symptom onset. If revascularization was not achieved, balloon angioplasty was performed, followed by stenting or temporary endovascular bypass was performed. The result in 15 cases was not so successful. Since then, we started using the thromboaspiration method as the first line treatment of the mechanical thrombolysis. Results : After using the thromboaspiration, we had better results in recanalization rate, modified Rankin Score (mRS) and reperfusion injury compared to AMCD. The recanalization rate was 80.85%, mRS is 2.85, and there was only 0.09% hemorrhagic formation. Conclusion : Even though thromboaspiration is not statistically significant due to the limited numbers of patients enrolled in this study, we think it is a good way in mechanical thronbolysis for hyperacute stroke.
#Aspiration #Mechanical #Stroke #Acute #Thrombolysis

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참고문헌 (17)

참고문헌 신청
Adams HP Jr / 2003 / Guidelines for the early management of patients with ischemic stroke : A scientific statement from the Stroke Council of the American Stroke Association / Stroke 34:1056~1083 google schola Barnwell SL / 1994 / Safety and efficacy of delayed intraarterial urokinase therapy with mechanical clot disruption for thromboembolic stroke / AJNR Am J Neuroradiol 15:1817~1822 google schola Burns TC / 2008 / Endovascular interventions following intravenous thrombolysis may improve survival and recovery in patients with acute ischemic stroke : a case-control study / AJNR Am J Neuroradiol 29:1918~1924 google schola Grunwald IQ / 2009 / Revascularization in acute ischemic stroke using the penumbra system : the first single center experience / Eur J Neurol 16:1216 google schola Hacke W / 2004 / Association of outcome with early stroke treatment : pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials / Lancet 363:768~774 google schola

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