지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Seizure is a foreseeable risk in patients with brain lesion. However, seizure during treating non-brain lesion is not a familiar situation to neurosurgeon. Posterior reversible encephalopathy syndrome (PRES) is a relatively common situation after systemic chemotherapy. The aim of this study is to make neurosurgeons aware of this potential medical problem. A 52-year-old woman with advanced gastric cancer, presented with low back pain due to spinal metastasis at the 4th lumbar vertebra. Ten cycles of chemotherapy with FOLFOX (5-Fluoruracil/Oxaliplatin) had been completed 23 days ago. Two days before the planned operation, a generalized tonic clonic seizure occurred. She did not have a history of hypertension or seizure. The seizure was stopped with lorazepam 4mg. The brain magnetic resonance (MR) imaging showed high signal changes in both parieto-occipital lobes on the T2-weighted images, and these were partially enhanced, suggesting PRES. The surgery was preceded by treatment with an antiepileptic drug. The MR images, taken 1.5 months after the seizure, showed that the lesion was no longer present. At 3 month follow-up, no additional seizure attack occurred without any seizure medication. The possibility of a seizure attack should be considered if the patient has a history of chemotherapy.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Bartynski WS / 2008 / Posterior reversible encephalopathy syndrome, part 1 : fundamental imaging and clinical features / AJNR Am J Neuroradiol 29:1036~1042
Bartynski WS / 2008 / Posterior reversible encephalopathy syndrome, part 2 : controversies surrounding pathophysiology of vasogenic edema / AJNR Am J Neuroradiol 29:1043~1049
장웅규 / 2009 / Clinical Results of Cyberknife® Radiosurgery for Spinal Metastases / 대한신경외과학회지 46(6):538~544
Choi SM / 2001 / 5-fluorouracil- induced leukoencephalopathy in patients with breast cancer / J Korean Med Sci 16:328~334
de Pontual L / 2009 / Epistasis between RET and BBS mutations modulates enteric innervation and causes syndromic Hirschsprung disease / Proc Natl Acad Sci U S A 106:13921~13926
Bartynski WS / 2008 / Posterior reversible encephalopathy syndrome, part 2 : controversies surrounding pathophysiology of vasogenic edema / AJNR Am J Neuroradiol 29:1043~1049
장웅규 / 2009 / Clinical Results of Cyberknife® Radiosurgery for Spinal Metastases / 대한신경외과학회지 46(6):538~544
Choi SM / 2001 / 5-fluorouracil- induced leukoencephalopathy in patients with breast cancer / J Korean Med Sci 16:328~334
de Pontual L / 2009 / Epistasis between RET and BBS mutations modulates enteric innervation and causes syndromic Hirschsprung disease / Proc Natl Acad Sci U S A 106:13921~13926
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