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논문 기본 정보

자료유형
학술저널
저자정보
Jung, Jong-Kwon (Department of Anesthesiology, Inha University Hospital) Oh, Chang-Hyun (Department of Anesthesiology, Seoul Regional Military Manpower Administration) Yoon, Seung-Hwan (Department of Neurosurgery, Inha Neural Repair Center) Ha, Yoon (Department of Neurosurgery, Yonsei Severance Hospital University) Park, So-Ra (Department of Neurosurgery, Inha University Hospital) Choi, Byung-Hyune (Department of Neurosurgery, Inha University Hospital)
저널정보
대한신경외과학회 대한신경외과학회지 대한신경외과학회지 제50권 제3호
발행연도
2011.1
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209 - 215 (7page)

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Objective : The authors investigated the changes of cortical sensorimotor activity in functional MRI (fMRI) and functional recovery in spinal cord injury (SCI) patients who had been treated by bone marrow cell transplantation. Methods : Nineteen patients with SCI were included in this study; ten patients with clinical improvement and nine without. The cortical sensorimotor activations were studied using the proprioceptive stimulation during the fMRI. Results : Diagnostic accuracy of fMRI with neurological improvement was 70.0% and 44.4% for sensitivity and specificity, respectively. Signal activation in the ipsilateral motor cortex in fMRI was commonly observed in the clinically neurological improved group (p-value=0.002). Signal activation in the contralateral temporal lobe and basal ganglia was more commonly found in the neurological unimproved group (p-value<0.001). Signal activation in other locations was not statistically different. Conclusion : In patients with SCI, activation patterns of fMRI between patients with neurologic recovery and those without varied. Such plasticity should be considered in evaluating SCI interventions based on behavioral and neurological measurements.

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