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논문 기본 정보

자료유형
학술저널
저자정보
Kiranmayi, Mangamuri Usha (Department of Botany and Microbiology, Acharya Nagarjuna University) Sudhakar, Poda (Department of Biotechnology, Acharya Nagarjuna University) Sreenivasulu, Kamma (Department of Biotechnology, K L University) Vijayalakshmi, Muvva (Department of Botany and Microbiology, Acharya Nagarjuna University)
저널정보
한국균학회 Mycobiology Mycobiology 제39권 제3호
발행연도
2011.1
수록면
174 - 181 (8page)

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The purpose of the present study was to investigate the influence of cultural and environmental parameters affecting the growth and bioactive metabolite production of the rare strain VUK-10 of actinomycete Pseudonocardia, which exhibits a broad spectrum of in vitro antimicrobial activity against bacteria and fungi. Production of bioactive metabolites by the strain was high the in modified yeast extract-malt extract-dextrose (ISP-2) broth, as compared to other tested media. Glucose (1%) and tryptone (0.25%) were found to be the most suitable carbon and nitrogen sources, respectively, for optimum production of growth and bioactive metabolites. Maximum production of bioactive metabolites was found in the culture medium with initial pH 7 incubated with the strain for four days at $30^{\circ}C$, under shaking conditions. This is the first report on the optimization of bioactive metabolites by Pseudonocardia sp. VUK-10.

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