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자료유형
학술저널
저자정보
Kim, Hyun-Kyu (Department of Dermatology, Chung-Ang University College of Medicine) Chang, Hui-Kyoung (AmorePacific R&D Center) Baek, Seok-Yun (AmorePacific R&D Center) Chung, Jin-Oh (AmorePacific R&D Center) Rha, Chan-Su (AmorePacific R&D Center) Kim, So-Young (Department of Convergence Medicine and Pharmaceutical Biosciences, Chung-Ang University College of Medicine) Kim, Beom-Joon (Department of Dermatology, Chung-Ang University College of Medicine) Kim, Myeung-Nam (Department of Dermatology, Chung-Ang University College of Medicine)
저널정보
한국균학회 Mycobiology Mycobiology 제40권 제2호
발행연도
2012.1
수록면
124 - 128 (5page)

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Multiple treatment modalities, including topical and systemic corticosteroid and phototherapy, have been used in treatment of patients with atopic dermatitis. However, long-term corticosteroid therapy may have various adverse effects. The purpose of this study was to investigate the therapeutic efficacy and safety of bath therapy using green tea extracts for treatment of patients with atopic dermatitis. A total of four patients with atopic dermatitis were enrolled in this study. A Malassezia multiplex detection kit was used in performance of multiplex PCR on clinical isolates, which confirmed Malassezia sympodialis. Subjects underwent treatment with bath therapy using green tea extracts three times per wk for a period of 4 wk. Assessment using the scoring atopic dermatitis (SCORAD) index, the visual analogue scale for pruritus, and transepidermal water loss was performed weekly. Laboratory tests were performed before and after treatment. All patients showed marked improvement on the mean SCORAD and visual analogue scale, and a significant decrease in the mean values of serum eosinophil counts was observed after treatment. Bath therapy with green tea extract is an effective, safe, and nonsteroidal therapy for treatment of patients with atopic dermatitis associated with Malassezia sympodialis.

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