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논문 기본 정보

자료유형
학술저널
저자정보
Yoon, Ki-Nam (Division of Life Sciences, University of Incheon) Lee, Jae-Seong (Division of Life Sciences, University of Incheon) Kim, Hye-Young (Division of Life Sciences, University of Incheon) Lee, Kyung-Rim (Division of Life Sciences, University of Incheon) Shin, Pyung-Gyun (Mushroom Division, National Institute of Horticultural and Herbal Science, Rural Development Administration) Cheong, Jong-Chun (Mushroom Division, National Institute of Horticultural and Herbal Science, Rural Development Administration) Yoo, Young-Bok (Mushroom Division, National Institute of Horticultural and Herbal Science, Rural Development Administration) Alam, Nuhu (Department of Botany, Jahangirnagar University) Ha, Tai-Moon (Mushroom Research Institute, Geonggi Agricultural Research and Extension Service) Lee, Tae-Soo (Division of Life Sciences, University of Incheon)
저널정보
한국균학회 Mycobiology Mycobiology 제39권 제4호
발행연도
2011.1
수록면
283 - 289 (7page)

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The wild edible mushroom, Lentinus lepideus has recently been cultivated for commercial use in Korea. While the mushroom has been widely used for nutritional and medicinal purposes, the possible anti-hyperlipidemic action is unclear. The effects of dietary L. lepideus on plasma and feces biochemical and on the liver histological status were investigated in hypercholesterolemic rats. Six-wk-old female Sprague-Dawley albino rats were divided into three groups of 10 rats each. Biochemical and histological examinations were performed. A diet containing 5% L. lepideus fruiting bodies reduced plasma total cholesterol, triglyceride, low-density lipoprotein, total lipid, phospholipids, and the ratio of low-density to high-density lipoprotein. Body weight was reduced. The diet did not adversely affect plasma biochemical and enzyme profiles. L. lepideus reduced significantly plasma ${\beta}$- and pre-${\beta}$-lipoprotein, while ${\alpha}$-lipoprotein content was increased. A histological study of hepatic cells by conventional hematoxylin-eosin and oil red O staining revealed normal findings for mushroom-fed hypercholesterolemic rats. The present study suggests that a diet supplemented with L. lepideus can provide health benefits by acting on the atherogenic lipid profile in hypercholesterolemic rats.

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