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Characteristics and Treatment Outcome of Intracranial Aneurysms in Children and Adolescents
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논문 기본 정보

Type
Academic journal
Author
Nam, Sun Mo (Department of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine) Jang, Donghwan (Department of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine) Wang, Kyu-Chang (Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul National University College of Medicine)
Journal
대한신경외과학회 대한신경외과학회지 대한신경외과학회지 제62권 제5호 SCOPUS
Published
2019.1
Pages
551 - 560 (10page)

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Characteristics and Treatment Outcome of Intracranial Aneurysms in Children and Adolescents
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Objective : Intracranial aneurysms are not common in young age patients. We sought to find the characteristics of the intracranial aneurysms in patients under 20 years of age. Methods : We reviewed 23 consecutive patients ${\leq}20$ years of age treated for their intracranial aneurysms during the period from 1995 to 2017. From medical records and imaging studies, we gathered data on age, sex, presentation, associated medical condition, location and characteristics of aneurysms, treatment and clinical outcomes. Results : The patients' ages ranged from 13 months to 20 years (median, 14 years). There were 16 males and seven females (male to female ratio, 2.3 : 1) with 31 aneurysms. Clinical presentations included sudden severe headache in 61%, followed by altered mentality in 17% and seizure in 17%. More than one-fourth patients had specific medical conditions related to the development of the cerebral aneurysms. The majority of aneurysms occurred in the anterior circulation (71%), and were saccular (71%). There were each three patients with false aneurysms (13%) and giant aneurysms (13%), and only one patient with multiple aneurysms (4%). We treated 22 patients : 21 aneurysms with the endovascular methods, three with open surgery, and one with combined treatment. Good functional outcome could be achieved in 86% during the follow-up period. Conclusion : In this series, the young-age patients with intracranial aneurysms were characterized by male predominance, related specific medical conditions, low incidence of multiple aneurysms, high incidence of giant aneurysms and good functional outcome after treatment.
#Aneurysm #Etiology #Pediatrics #Risk factors #Treatment outcome

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Agid R / 2005 / The role of endovascular treatment for pediatric aneurysms / Childs Nerv Syst 21:1030~1036 google schola Ahn JH / 2010 / A ruptured middle cerebral artery aneurysm in a 13-month-old boy with Kawasaki disease / J Neurosurg Pediatr 6:150~153 google schola Beslow LA / 2010 / Pediatric stroke: the importance of cerebral arteriopathy and vascular malformations / Childs Nerv Syst 26:1263~1273 google schola Bigi S / 2011 / Acute ischemic stroke in children versus young adults / Ann Neurol 70:245~254 google schola Bober MB / 2017 / Microcephalic osteodysplastic primordial dwarfism, type II: a clinical review / Curr Osteoporos Rep 15:61~69 google schola

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