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논문 기본 정보

자료유형
학술저널
저자정보
Yang, Ji-Yeon (Department of Bioenvironmental Chemistry and Institute of Agricultural Science & Technology, Chonbuk National University) Lee, Hoi-Seon (Department of Bioenvironmental Chemistry and Institute of Agricultural Science & Technology, Chonbuk National University)
저널정보
한국응용생명화학회 Applied Biological Chemistry Applied Biological Chemistry 제55권 제4호
발행연도
2012.1
수록면
485 - 489 (5page)

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Antioxidant and antibacterial activities of materials isolated from the methanol extract of mulberry fruits were evaluated. The active constituent of the methanol extract derived from mulberry fruits was isolated by silica gel and LH-20 column chromatographies and was identified as morin by electron ionization mass spectrometer, $^1H$-NMR, and $^{13}C$-NMR spectroscopy. Based on the $IC_{50}$ values, the antioxidant activities of morin exhibited potent inhibition according to 1,1-diphenyl-2-picrylhydrazyl ($30.0{\mu}g/mL$) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) ($71.0{\mu}g/mL$) radical scavenging assays. Furthermore, the antibacterial activity of morin showed moderate (++) inhibition against Streptococcus mutans at both 5 and 2 mg/disc, according to paper disc diffusion assays, indicating morin isolated from mulberry fruits could be a useful natural agent for the management of antioxidant and antibacterial treatments.

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