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자료유형
학술저널
저자정보
Boo, Kyung-Hwan (College of Applied Life Science, Jeju National University) Lee, Do-Seung (College of Applied Life Science, Jeju National University) Woo, Jin-Kyu (College of Applied Life Science, Jeju National University) Ko, Seung-Hee (College of Applied Life Science, Jeju National University) Jeong, Eun-Hyoung (College of Applied Life Science, Jeju National University) Hong, Quan-Chun (Department of Life Science, Shangqiu Normal University) Riu, Key Zung (College of Applied Life Science, Jeju National University) Lee, Dong-Sun (College of Applied Life Science, Jeju National University)
저널정보
한국응용생명화학회 Applied Biological Chemistry Applied Biological Chemistry 제54권 제1호
발행연도
2011.1
수록면
132 - 135 (4page)

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Methanol extracts of Paeonia lactiflora roots (Radix Paeaniae Lactiflora) had antibacterial activity against Bacillus subtilis. These extracts generated superoxide radicals in the B. subtilis lysate. However, the radicals were strongly detoxified by the addition of superoxide dismutase, an indication that superoxide radicals are important in the antibacterial actions of the extracts. The root extracts also showed a pivotal inhibition role in trafficking of viral glycoprotein in virusinfected baby hamster kidney (BHK) cells. The methanol extract effectively inhibited syncytium formation in a concentration-dependent, and it did not affect glycoprotein synthesis. These results suggest that oxygen radical affect the transport process of viral glycoprotein without its synthesis.

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