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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 347 - 362 (16page)
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초록· 키워드
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Marine sponges have been considered as a drug treasure house with respect to great potential regarding their secondary metabolites. Most of the studies have been conducted on sponge's derived compounds to examine its pharmacological properties. Such compounds proved to have antibacterial, antiviral, antifungal, antimalarial, antitumor, immunosuppressive, and cardiovascular activity. Although, the mode of action of many compounds by which they interfere with human pathogenesis have not been clear till now, in this review not only the capability of the medicinal substances have been examined in vitro and in vivo against serious pathogenic microbes but, the mode of actions of medicinal compounds were explained with diagrammatic illustrations. This knowledge is one of the basic components to be known especially for transforming medicinal molecules to medicines. Sponges produce a different kind of chemical substances with numerous carbon skeletons, which have been found to be the main component interfering with human pathogenesis at different sites. The fact that different diseases have the capability to fight at different sites inside the body can increase the chances to produce targeted medicines.
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등록된 정보가 없습니다.
참고문헌 (157)
참고문헌 신청
Amade, P / 1987 / Antimicrobial activity of marine sponges of Mediterranean / Sea. Mar. Biol 94:271~275
Amade, P. H / 1982 / Antimicrobial activities of marine from French Polynesia and Brittany / Mar. Biol 70:223~228
Amigó, M / 2007 / Synthesis and evaluation of diverse thio avarol derivatives as potential UVB photoprotective candidates / Bioorg. Med. Chem. Lett 17:2561~2565
Ang, K. K / 2001 / Immunemediated parasite clearance in mice infected with Plasmodium berghei following treatment with manzamine A / Parasitol. Res 87:715~721
Arimoto, H / 1998 / Absolute stereochemistry of halichlorine; a potent inhibitor of VCAM-1induction / Tetrahedron Lett 39:861~862
Amade, P. H / 1982 / Antimicrobial activities of marine from French Polynesia and Brittany / Mar. Biol 70:223~228
Amigó, M / 2007 / Synthesis and evaluation of diverse thio avarol derivatives as potential UVB photoprotective candidates / Bioorg. Med. Chem. Lett 17:2561~2565
Ang, K. K / 2001 / Immunemediated parasite clearance in mice infected with Plasmodium berghei following treatment with manzamine A / Parasitol. Res 87:715~721
Arimoto, H / 1998 / Absolute stereochemistry of halichlorine; a potent inhibitor of VCAM-1induction / Tetrahedron Lett 39:861~862
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