지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 21 - 34 (14page)
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A visual analysis approach and the developed supporting technology provide a comprehensive solution for analyzing large and complex integrated genomic and biomedical data. This paper presents a methodology that is implemented as an interactive visual analysis technology for extracting knowledge from complex genetic and clinical data and then visualizing it in a meaningful and interpretable way. By synergizing the domain knowledge into development and analysis processes, we have developed a comprehensive tool that supports a seamless patient-to-patient analysis, from an overview of the patient population in the similarity space to the detailed views of genes. The system consists of multiple components enabling the complete analysis process, including data mining, interactive visualization, analytical views, and gene comparison. We demonstrate our approach with medical scientists on a case study of childhood cancer patients on how they use the tool to confirm existing hypotheses and to discover new scientific insights.
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참고문헌 (33)
참고문헌 신청
Goronzy JJ / 2004 / Prognostic markers of radiographic progression in early rheumatoid arthritis / Arthritis Rheum 50:43~54
Yeoh EJ / 2002 / Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling / Cancer Cell 1:133~143
Flotho C / 2007 / A set of genes that regulate cell proliferation predicts treatment outcome in childhood acute lymphoblastic leukemia / Blood 110:1271~1277
McLachlan GJ / 2008 / Large-scale simultaneous inference with applications to the detection of differential expression with microarray data / Statistica 68:1190~30
Jolliffe IT / 2002 / Principle Component Analysis / Springer
Yeoh EJ / 2002 / Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling / Cancer Cell 1:133~143
Flotho C / 2007 / A set of genes that regulate cell proliferation predicts treatment outcome in childhood acute lymphoblastic leukemia / Blood 110:1271~1277
McLachlan GJ / 2008 / Large-scale simultaneous inference with applications to the detection of differential expression with microarray data / Statistica 68:1190~30
Jolliffe IT / 2002 / Principle Component Analysis / Springer
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