Efficacy of Postoperative Bladder Irrigation with Water for Injection in Reducing Recurrence Rates of Non Muscle Invasive Bladder Cancer

Grivas, Nikolaos; Hastazeris, Konstantinos; Kafarakis, Vasileios; Tsimaris, Ioannis; Aspiotis, Spiridon; Stratis, Antonios; Stavropoulos, Nikolaos Efthimios

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저자정보: Grivas, Nikolaos (General Hospital, Department of Urology, Makriyianni Avenue, Ioannina, Perfecture of Epirus) Hastazeris, Konstantinos (General Hospital, Department of Urology, Makriyianni Avenue, Ioannina, Perfecture of Epirus) Kafarakis, Vasileios (General Hospital, Department of Urology, Makriyianni Avenue, Ioannina, Perfecture of Epirus) Tsimaris, Ioannis (General Hospital, Department of Urology, Makriyianni Avenue, Ioannina, Perfecture of Epirus) Aspiotis, Spiridon (General Hospital, Department of Urology, Makriyianni Avenue, Ioannina, Perfecture of Epirus) Stratis, Antonios (General Hospital, Department of Urology, Makriyianni Avenue, Ioannina, Perfecture of Epirus) Stavropoulos, Nikolaos Efthimios (General Hospital, Department of Urology, Makriyianni Avenue, Ioannina, Perfecture of Epirus)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제5호

발행연도: 2014.1

수록면: 2,263 - 2,266 (4page)

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The aim of the study was to investigate the results of bladder irrigation with Water for Injection (WFI) after transurethral resection of bladder tumours for comparison with those for adjuvant use of BCG. A total of 239 patients (158 with single tumours, group A, and 81 with multiple tumours, group B) received continuous intravesical postoperative irrigation with WFI. Some 128 patients received intravesical irrigation with WFI, followed by weekly instillations of BCG (group C). Recurrence-free rate (RFR) and recurrence-free intervals (RFI) were recorded. RFR for those patients who received only intravesical irrigation with WFI (groups A and B) was 75.8%, 66.2% and 63.2% at the 1st, 2nd and 3rd year of follow up, respectively. Corresponding rates for group C were 61.7%, 55.4% and 49%. Median RFI in group B were 18, 11, 15, 15 and 12 months for Ta, T1, grade 1, grade 2 and grade 3 tumours, respectively. In group C corresponding intervals were 20, 33, 8, 20 and 42 months. BCG improved RFR only in T1 (p=0.014) and grade 3 tumours (p=0.007). In conclusion, postoperative bladder irrigation with WFI could increase RFR during the first and second year of follow up.

#Bladder tumors #BCG #tumor recurrence #bladder irrigation

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Grivas, Nikolaos

소속기관 General Hospital, Department of Urology, Makriyianni Avenue, Ioannina, Perfecture of Epirus