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자료유형
학술저널
저자정보
Guettiti, Haifa (Department of Pathology, Faculty of Medicine, Institut Pasteur de Tunis) Ennaifer, Emna (Department of Pathology, Faculty of Medicine, Institut Pasteur de Tunis) Attia, Leila (Department of Gynecology Charles Nicolle Hospital Tunis) Chelly, Dalenda (Department of Gynecology Centre de maternite et de Neonatologie Tunis) Alaya, Nissaf Ben (Department of Epidemiology, Observatoire National de Tunis) Aissa, Rim Ben (Family Planning Clinic of Ariana Tunis) Laassili, Thalja (Department of Pathology, Faculty of Medicine, Institut Pasteur de Tunis) Boubaker, Samir (Department of Pathology, Faculty of Medicine, Institut Pasteur de Tunis)
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제21호
발행연도
2014.1
수록면
9,361 - 9,365 (5page)

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Background: To estimate the pre-vaccination distribution of human papillomavirus (HPV) types among women from urban Tunis. Materials and Methods: A total of 611 women aged 18-69 years were enrolled in three local gynaecological outpatient departments. All underwent a gynaecological examination with Pap test and dry swab for HPV detection and typing performed by linear array genotyping test (Roche). Cytological examination was conducted on conventional Pap smears. Results: HPV DNA was found in 6.5% of the women; the most frequent HPV types were HPV 16 and HPV 11 at 3.27% and 1.96%, respectively. The second most frequent high risk (HR) HPV type was HPV 58 (0.82%) followed by HPV 18, HPV 31 and HPV 33 found in only 0.33% of women. Single infections with HPV types, targeted by the quadrivalent vaccine (6, 11, 16, and 18), were detected in 3.6 % of the study patients (55% of positive women). HPV infection was found in 3.83% of women with normal cytology and in 47.4% of women with cytological abnormalities. No statistically significant trend in prevalence by age group emerged for any HPV type or for high or low risk types. Conclusions: These data show a relatively low prevalence of HPV infection in women from urban Tunis with a high proportion of HPV16 and HPV58. This should be considered in the upcoming screening programs and vaccination strategy.

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