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논문 기본 정보

자료유형
학술저널
저자정보
Liu, Hao (Department of Pathology, Nanfang Hospital & School of Basic Medical Sciences, Southern Medical University) Wang, Bin (Department of Pathology, Nanfang Hospital & School of Basic Medical Sciences, Southern Medical University) Lin, Jie (Department of Pathology, Nanfang Hospital & School of Basic Medical Sciences, Southern Medical University) Zhao, Liang (Department of Pathology, Nanfang Hospital & School of Basic Medical Sciences, Southern Medical University)
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제21호
발행연도
2014.1
수록면
9,059 - 9,064 (6page)

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MicroRNAs (miRNAs) are ubiquitously expressed small, non-coding RNAs that negatively regulate gene expression at a post transcriptional/translational level. They have emerging as playing crucial roles in cancer at all stages ranging from initiation to metastasis. As a tumor suppressor miRNA, aberrant expression of microRNA-29b (miR-29b) has been detected in various types of cancer, and its disturbance is related with tumor development and progression. In this review, we summarize the latest findings with regard to the tumor suppressor signatureof miR-29b and its regulatory mechanisms. Our review highlights the diverse relationships between miR-29b and its target genes in malignant tumors.

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