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자료유형
학술저널
저자정보
Yildirim, Mustafa (Department of Medical Oncology, Ministry of Health Batman Regional Govermant Hospital) Demirpence, Ozlem (Department of Biochemistry, Ministry of Health Batman Regional Govermant Hospital) Kaya, Vildan (Department of Radiation Oncology, Suleyman Demirel University) Suren, Dinc (Department of Pathology, Antalya Education and Research Hospital) Karaca, Mehmet (Department of Obstetrics and Gynecology, Antalya Education and Research Hospital) Evliyaoglu, Osman (Department of Biochemistry, Ministry of Health Batman Regional Govermant Hospital) Yilmaz, Necat (Department of Biochemistry, Antalya Education and Research Hospital) Gunduz, Seyda (Department of Medical Oncology, Antalya Education and Research Hospital)
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제15호
발행연도
2014.1
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6,233 - 6,237 (5page)

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Background: Intraperitoneal spread of gynecologic cancers is a major cause of mortality and morbidity and often presents with malignant ascites. Microscopic tumor spread can be demonstrated by a peritoneal wash cytology and help assess the prognosis of the disease. In our study, the roles of paraoxonase and ceruloplasmin, measured in peritoneal washing fluid of patients operated for gynecologic pathologies in differential diagnosis was investigated. Materials and Methods: Patients operated for malign or benign gynecologic pathologies in Antalya Education and Research Hospital Gynecology Clinic between 2010-2012 were included in the study. Samples were obtained during surgery. Results: A statistically significant difference was detected between patients with benign and malign diseases with regards to PON1 levels measured in peritoneal washing fluid (p:0.044), the average values being $64.2{\pm}30.8$ (Range 10.8-187.2) and $41.4{\pm}21.4$ (Range 10.4-95.5), respectively. No significant variation was evident for ceruloplasmin. Conclusions: Paraoxonase levels measured in peritoneal washing fluid may contribute to the differentiation of malign-benign diseases in gynecologic pathologies.

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