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학제간연구 과학기술학 뇌인지과학 기술정책 기타 복합학

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논문 기본 정보

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학술저널
저자정보
Kim, Young-Soo (Department of Neurosurgery, Medical Research Institute, Pusan National University Hospital) Han, In-Ho (Department of Neurosurgery, Medical Research Institute, Pusan National University Hospital) Lee, In-Sook (Department of Radiology, Medical Research Institute, Pusan National University Hospital) Lee, Jung-Sub (Department of Orthopedic Surgery, Medical Research Institute, Pusan National University Hospital) Choi, Byung-Kwan (Department of Neurosurgery, Medical Research Institute, Pusan National University Hospital)
저널정보
대한신경외과학회 대한신경외과학회지 대한신경외과학회지 제52권 제2호
발행연도
2012.1
수록면
126 - 132 (7page)

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Objective : The purpose of this study was to present the MRI and CT findings of solitary spinal bone lesions (SSBLs) with the aims of aiding the differential diagnoses of malignant tumors and benign lesions, and proposing a diagnostic strategy for obscure SSBLs. Methods : The authors retrospectively reviewed the imaging findings of 19 patients with an obscure SSBL on MRI at our hospital from January 1994 to April 2011. The 19 patients were divided to benign groups and malignant groups according to final diagnosis. MRI and CT findings were evaluated and the results of additional work-up studies were conducted to achieve a differential diagnosis. Results : At final diagnoses, 10 (52.6%) of the 19 SSBLs were malignant tumors and 9 (47.4%) were benign lesions. The malignant tumors included 6 metastatic cancers, 3 multiple myelomas, and 1 chordoma, and the benign lesions included 4 osteomyelitis, 2 hemangiomas, 2 nonspecific chronic inflammations, and 1 giant cell tumor. No MRI characteristics examined was found to be significantly different in the benign and malignant groups. Reactive sclerotic change was observed by CT in 1 (10.0%) of the 10 malignant lesions and in 7 (77.8%) of the 9 benign lesions (p=0.005). Conclusion : Approximately half of the obscure SSBLs were malignant tumors. CT and MRI findings in combination may aid the differential diagnosis of obscure SSBLs. In particular, sclerotic change on CT images was an important finding implying benign lesion. Finally, we suggest a possible diagnostic strategy for obscure SSBLs on MRI.
#Solitary spinal bone lesion #Differential diagnosis #MRI #CT #benign lesion #Malignant lesion

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참고문헌 (18)

참고문헌 신청
Abdel Razek AA / 2010 / Imaging appearance of primary bony tumors and pseudo-tumors of the spine / J Neuroradiol 37:37~50 google schola Aebi M / 2003 / Spinal metastasis in the elderly / Eur Spine J 12(Suppl 2):202~213 google schola Destombe C / 2007 / Investigations for bone metastasis from an unknown primary / Joint Bone Spine 74:85~89 google schola Dunbar JA / 2010 / The MRI appearances of early vertebral osteomyelitis and discitis / Clin Radiol 65:974~981 google schola Erlemann R / 2006 / Imaging and differential diagnosis of primary bone tumors and tumor-like lesions of the spine / Eur J Radiol 58:48~67 google schola

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