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논문 기본 정보

자료유형
학술저널
저자정보
문효정 (원광대학교 의과대학 재활의학과, 원광의과학연구소) 이수경 (원광대학교 한의대학 한방재활의학과) 노세응 (원광대학교 의과대학 재활의학과, 원광의과학연구소) 주민철 (원광대학교 의과대학 재활의학과, 원광의과학연구소)
저널정보
한방재활의학과학회 한방재활의학과학회지 한방재활의학과학회지 제26권 제2호
발행연도
2016.1
수록면
97 - 103 (7page)

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Objectives To evaluate the effects and safety of the aqueous extract of the dried, immature fruit of Poncirus trifoliate (L.) Raf. (Rutaceae) (PF) in stroke patients with constipation. Methods A total of 22 patients were recruited. Patients were interviewed about the clinical informations, constipation score and Bristol stool form scale at twice, before intake PF and after intake PF 2 weeks. The total and segmental colon transit time (CTT) were measured by using radio-opaque markers (Kolomark$^{(R)}$). The degree of stool retention was evaluated by the plain abdominal radiography and was scored by Leech score. Results Before intake PF, constipation scores ranged from 3 to 12, average $6.54{\pm}2.87$ and Bristol stool form scale ranged from 1 to 6, average $3.86{\pm}1.21$. CTTs were $9.05{\pm}6.89hours$, $14.29{\pm}10.68hours$, $12.11{\pm}7.19hours$ and $35.40{\pm}19.5hours$ in the right, left, rectosigmoid and total colon, respectively. Stool retention score was $2.45{\pm}0.61$, $2.3{\pm}0.86$, $1.9{\pm}0.85$, $6.65{\pm}1.56$ in the right, left, rectosigmoid and total colon, respectively. After 2 weeks, constipation scores ranged from 2 to 8, average $4.28{\pm}2.05$ and Bristol stool form scale ranged from 1 to 6, average $4.17{\pm}1.04$. CTTs were $7.41{\pm}8.86hours$, $11.12{\pm}9.12 hours$, $8.83{\pm}8.75hours$ and $27.3{\pm}20.2$ hours in the right, left, rectosigmoid and total colon, respectively. Stool retention score was $1.9{\pm}0.64$, $2.2{\pm}0.69$, $1.4{\pm}0.88$, $5.5{\pm}1.39$ in the right, left, rectosigmoid and total colon, respectively. There were statistically significant difference in the total and rectosigmoid colon CTT and constipation score, Stool retention score in right and rectosigmoid colon (p<0.05) after PF therapy. Conclusions These results suggest potential for PF therapy in stroke patient with constipation.

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