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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 경희한의학연구센터 Oriental pharmacy and experimental medicine Oriental pharmacy and experimental medicine 제11권 제3호
- 발행연도
- 2011.1
- 수록면
- 143 - 146 (4page)
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초록· 키워드
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The ethanol extract of the dried rhizome of Alocasia indica (Roxb.) Schott. (Family - Araceae) was investigated for its possible analgesic and anti-inflammatory activities in animal models. The extract showed significant ($P$ <0.001) writhing inhibition in acetic acid-induced writhing in mice at the oral dose of 300 and 600 mg/kg of body weight comparable to the standard drug diclofenac sodium at the dose of 25 mg/kg of body weight. Moreover, when given orally to rats at dose of 300 and 600 mg/kg of body weight, the extract showed a significant ($P$ <0.001) anti-inflammatory activity against carrageenin induced paw edema in rats which was comparable to the standard drug aspirin at the dose of 150 mg/kg of body weight. The overall results tend to suggest the analgesic and anti-inflammatory activities of the crude ethanolic extract of dried rhizome of $Alocasia$ $indica$ ($Roxb.$) $Schott$. The obtained results provide a support for the use of this plant in traditional medicine and its further investigation.
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