지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 55 - 63 (9page)
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초록· 키워드
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Objectives : The solvent extracts of Pruni persicae Flos were investigated for the activities of anti-oxidant and anti-inflammatory effects to apply as a functional ingredient for cosmetic products. Methods : In this study, the fractions of P. persicae Flos were extracted with 70.0% acetone and purified using Sephadex LH-20 column chromatography. As a result, eight fractions were isolated. We performed MTT assay, total polyphenol contents, DPPH free radical scavenging assay, SOD-like activity, xanthine oxidase inhibition assay, astringent activity assay, hyaluronidase inhibition assay and the production of nitric oxide. Results : For anti-oxidant effects, the electron donating ability of fraction (Fr.) 2-5, Fr.-8 isolated from P. persicae Flos was above 90.0% at 100 ppm respectively. The superoxide dismutase (SOD) - like activity of Fr.-5 isolated from P. persicae Flos was 92.1% at 1,000 ppm. The xanthine oxidase inhibitory effect of Fr.-6 isolated from P. persicae Flos was about 83.3% at 1,000 ppm. Hyaluronidase inhibition activity related to the anti-inflammation effect was 94.0% for Fr.-4 isolated from P. persicae Flos at 500 ppm. In the anti-inflammation effect, the Fr.-4 isolated from P. persicae Flos inhibited the generation of nitric oxide. Conclusions : All these findings suggested that the fractions of P. persicae Flos has a great potential as a cosmeceutical ingredient with a anti-oxidant and anti-inflammatory effects.
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참고문헌 (46)
참고문헌 신청
김충현 / 2003 / 바위솔 추출물의 항산화활성 및 암세포 증식억제 / 한국약용작물학회지 11(1):31~39
Guo DA. / 2006 / Quality control of herbal medicines and their related products / Korean J Crop Sci 51:55~59
Miyake T. / 1988 / Active oxygen and oxidative stress / Masui 37(2):137
Videla LA. / 1988 / Biochemical aspects of cellular oxidative stress / Arch Biol Med Exp(Santiago) 21(1):85~92
Misra HP. / 1972 / The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase / J Biol Chem 247(10):3170~3175
Guo DA. / 2006 / Quality control of herbal medicines and their related products / Korean J Crop Sci 51:55~59
Miyake T. / 1988 / Active oxygen and oxidative stress / Masui 37(2):137
Videla LA. / 1988 / Biochemical aspects of cellular oxidative stress / Arch Biol Med Exp(Santiago) 21(1):85~92
Misra HP. / 1972 / The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase / J Biol Chem 247(10):3170~3175
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