지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 39 - 55 (17page)
이용수
초록· 키워드
오류제보하기
Objectives : Recently there have been encouraging results, from a western perspective, in the cancer research field regarding the anticancer effects of herbal medicine. This paper was aimed to review herbal medicine playing its anticancer role in terms of apoptosis, inflammation control, differentiation and telomerase. Methods : New studies for tang, medicinal herb itself or effective ingradients of medicinal herb showing anti-cancer effectiveness were reviewed and summarized in terms of pharmacological action. Results : Ethanol extracts of $Spatholobus$ $suberectus$ greatly inhibited cancer cell growth inducing cell apoptosis and cytotoxic effects. $Scutellaria$ $baicalensis$ may be responsible for its anticancer activity showing inhibition of $PGE_2$ synthesis via suppression of COX-2 expression. Saikosaponins isolated from $Bupleurum$ induced the differentiation of C6 glioma cells, cancer cells, into astrocytes, normal cells. Acetone extract of $Bupleurum$ $scorzonerifolium$ inhibited proliferation of human lung cancer cells via inducing apoptosis and suppressing telomerase activity. Conclusions : Herbal medicine inhibited cancer cell growth inducing cell apoptosis and cytotoxic effects. Inflammation persisting for a decade eventually elevates the risk of cancer sufficiently that it is discernible in case control epidemiological studies. Differentiation therapy is defined as a therapy to treat cancers by inducing differentiation of the stem cells. Telomerase expression is a hallmark of cancer. Nearly the complete spectrum of human tumors has been shown to be telomerase positive.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Li XJ. / 2007 / Western-medicine-validated anti-tumor agents and traditional Chinese medicine / Trends Mol Med 14(1):1~2
Kessler RC. / 2001 / Long-term trends in the use of complementary and alternative medical therapies in the United States / Ann Intern Med 135(4):262~268
Dobos GJ. / 2005 / Are national quality standards for traditional Chinese herbal medicine sufficient? : Current governmental regulations for traditional Chinese herbal medicine in certain Western countries and China as the Eastern origin country / Complement Ther Med 13(3):183~190
RUAN WJ. / 2006 / Anticancer effects of Chinese herbal medicine, science or myth? / J Zhejiang Univ Science B 7(12):1006~1014
Yang J. / 2004 / Hamrick, Penelope J. Duerksen-Hughes, Ying-Nian Y. ATM and ATR : Sensing DNA damage / World J Gastroenterol 10(2):155~160
Kessler RC. / 2001 / Long-term trends in the use of complementary and alternative medical therapies in the United States / Ann Intern Med 135(4):262~268
Dobos GJ. / 2005 / Are national quality standards for traditional Chinese herbal medicine sufficient? : Current governmental regulations for traditional Chinese herbal medicine in certain Western countries and China as the Eastern origin country / Complement Ther Med 13(3):183~190
RUAN WJ. / 2006 / Anticancer effects of Chinese herbal medicine, science or myth? / J Zhejiang Univ Science B 7(12):1006~1014
Yang J. / 2004 / Hamrick, Penelope J. Duerksen-Hughes, Ying-Nian Y. ATM and ATR : Sensing DNA damage / World J Gastroenterol 10(2):155~160
이 논문의 저자 정보
최근 본 자료
댓글(0)
0