메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Kim, Hyun-Ju (Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University) Um, Jae-Young (Department of Pharmacology, College of Korean Medicine, Institute of Korean Medicine, Kyung Hee University) Kim, Yun-Kyung (Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University)
저널정보
경희한의학연구센터 Oriental pharmacy and experimental medicine Oriental pharmacy and experimental medicine 제12권 제4호
발행연도
2012.1
수록면
307 - 312 (6page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Epidemiological studies have demonstrated that the glutathione S-transferase (GST) null genotype is related to an increased susceptibility to diseases associated with several types of cancer. This study investigated the risk of developing gastric or colorectal cancer related to the GST polymorphisms in the Korean population. Genotyping was performed on the subjects including 102 subjects with gastric cancer (GC), 172 subjects with colorectal cancer (CRC), and 200 healthy subjects as the control group. As a result, the GST theta1 (GSTT1) null genotype was associated with a 1.5-fold increased risk of developing CRC (95 % confidence interval (CI)=1.1-2.3, P=0.04). A significant association was found between the CRC and the combined genotypes of the GST mu1 (GSTM1) and GSTT1 (odds ratio02.1, 95 % CI=1.1-4.2, P=0.03). There were no significant associations between the GST polymorphisms and the GC subjects. These results suggest that the GSTT1 null genotype is associated with an increase in the risks of CRC in the Korean population.

목차

등록된 정보가 없습니다.

참고문헌 (0)

참고문헌 신청

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0