지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Objectives : The aim of this study was to examine the effects of brain-derived neurotrophic factor (BDNF) genetic polymorphism and job stress on the severity of alcohol drinking. It was hypothesized that individuals with the Met/Met BDNF genotype would be more vulnerable than those carrying the Val allele. Methods : Participants were 133 healthy Korean adults (mean age $28.2{\pm}1.1$). Job stress and the severity index of drinking were investigated through self-reported questionnaires. BDNF (rs6265) gene was genotyped. Results : There was no significant association between job stress and the severity of alcohol drinking. Although the severity of alcohol drinking was not associated with BDNF genetic polymorphism, there was a significant difference in men according to genotype and job stress. Men with homozygous BDNF Met allele were more severe in alcohol drinking when job stress was high, less severe in alcohol drinking when job stress was low than those carrying the Val allele (F = 4.47, p = 0.038). Also higher level of job stress was correlated with higher severity of alcohol drinking in men homozygous for BDNF Met allele (rs = 0.620, p = 0.005). Conclusions : These findings suggest the possibility that Met allele could have differential susceptibility, with men homozygous for BDNF Met allele being more susceptible to both more adverse and less adverse environmental influences.
목차
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참고문헌 (19)
참고문헌 신청
최승희 / 2001 / 서울 지역 사무직 근로자의 음주에 관한 형태 및 관련요인에 관한 조사 연구 / 보건교육건강증진학회지 18(2):27~44
Cooper ML / 1990 / Work stress and alcohol effects: a test of stress-induced drinking / J Health Soc Behav 31:260~276
Kang KH / 2001 / The relationship between alcohol use and job stress among firemen / Korean J Occup Environ Med 13:401~412
권구영 / 2005 / 직장인의 음주에 영향을 미치는 요인에 관한 연구 : 사무직 직장인을 중심으로 / 한국사회복지학 57(2):93~118
Hagihara A / 2000 / Work stressors and alcohol consumption among white-collar workers: a signal detection approach / J Stud Alcohol 61:462~465
Cooper ML / 1990 / Work stress and alcohol effects: a test of stress-induced drinking / J Health Soc Behav 31:260~276
Kang KH / 2001 / The relationship between alcohol use and job stress among firemen / Korean J Occup Environ Med 13:401~412
권구영 / 2005 / 직장인의 음주에 영향을 미치는 요인에 관한 연구 : 사무직 직장인을 중심으로 / 한국사회복지학 57(2):93~118
Hagihara A / 2000 / Work stressors and alcohol consumption among white-collar workers: a signal detection approach / J Stud Alcohol 61:462~465
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