지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Objectives : Although there have been studies that examine sex differences of the brain structures using magnetic resonance imaging, studies that specifically investigate cerebellar structural differences between men and women are scarce. The purpose of current study was to examine sex differences in structures of the cerebellum using cerebellar template and cerebellum analysis methods. Methods : Sixteen men and twenty women were included in the study. A MATLAB based program (MathWorks, Natick, MA, USA), Statistical Parametric Mapping 5 (SPM5) using the spatially unbiased infra-tentorial atlas template (SUIT) as the cerebellum template, was used to analyze the brain imaging data. Results : There was no significant difference in age between men (mean age=28.1) and women (mean age=27.2). Men showed higher gray matter density than women in two left cerebellar areas including the clusters in the lobules IV and V (a cluster located across the lobules IV and V), and the lobule VIIIb (lobules IV and V, t=4.75, p<0.001 ; lobule VIIIb, t=3.08, p=0.004). Conclusions : The current study found differences in cerebellar gray matter density between men and women. The current study holds its significance for applying the template specifically developed for the analysis of cerebellum.
목차
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참고문헌 (38)
참고문헌 신청
Chen X / 2007 / Sex differences in regional gray matter in healthy individuals aged 44-48 years: a voxel-based morphometric study / Neuroimage 36:691~699
Sowell ER / 2007 / Sex differences in cortical thickness mapped in 176 healthy individuals between 7 and 87 years of age / Cereb Cortex 17:1550~1560
Lv B / 2010 / Gender consistency and difference in healthy adults revealed by cortical thickness / Neuroimage 53:373~382
Rijpkema M / 2012 / Normal sexual dimorphism in the human basal ganglia / Hum Brain Mapp 33:1246~1252
Raz N / 2001 / Age and sex differences in the cerebellum and the ventral pons: a prospective MR study of healthy adults / AJNR Am J Neuroradiol 22:1161~1167
Sowell ER / 2007 / Sex differences in cortical thickness mapped in 176 healthy individuals between 7 and 87 years of age / Cereb Cortex 17:1550~1560
Lv B / 2010 / Gender consistency and difference in healthy adults revealed by cortical thickness / Neuroimage 53:373~382
Rijpkema M / 2012 / Normal sexual dimorphism in the human basal ganglia / Hum Brain Mapp 33:1246~1252
Raz N / 2001 / Age and sex differences in the cerebellum and the ventral pons: a prospective MR study of healthy adults / AJNR Am J Neuroradiol 22:1161~1167
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