지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Objective It has been suggested that the dopamine D2 receptor gene (DRD2) is associated with pathological gambling (PG). We investigated the association of the DRD2 Taq1A polymorphism and the temperament in PG using Cloninger's temperament and characteristic inventory (TCI). Methods 104 PG patients and 114 control subjects were recruited. Tests for DRD2 Taq1A polymorphism were conducted in both PG patients and controls. PG patients were requested to complete the TCI. Results There were no significant differences in frequencies of the genotype (${\chi}^2$ = 0.77, p = 0.681), allele (${\chi}^2$ = 0.52, p = 0.469), and allele (A1) carrier (${\chi}^2$ = 0.15, p = 0.695) between the PG patients and the control group. When we compared the TCI profile in the PG patients according to genotypes, there were significant differences in harm-avoidance (HA, p = 0.033), and self-directedness (SD, p = 0.012) among genotypes. These difference were more evident between A1 allele carriers and non-carriers (HA, p = 0.009 and SD, p = 0.004). Conclusion Present results suggest Taq1A polymorphism may not play an important role in the susceptibility to pathological gambling in our population. However, Taq1A polymorphism might be associated with some temperament in Korean PG patients.
목차
등록된 정보가 없습니다.
참고문헌 (57)
참고문헌 신청
Association AP / 1994 / Diagnostic and statistical manual of mental disorders.4th ed / American Psychiatric Press
Potenza MN / 2006 / Should addictive disorders include non-substance-related conditions / Addiction 101:142~151
Shaffer HJ / 1999 / Estimating the prevalence of disordered gambling behavior in the United States and Canada: a research synthesis / Am J Public Health 89:1369~1376
Braverman J / 2010 / How do gamblers start gambling: identifying behavioural markers for high-risk internet gambling / Eur J Public Health
Black DW / 2006 / A family study of pathological gambling / Psychiatry Res 141:295~303
Potenza MN / 2006 / Should addictive disorders include non-substance-related conditions / Addiction 101:142~151
Shaffer HJ / 1999 / Estimating the prevalence of disordered gambling behavior in the United States and Canada: a research synthesis / Am J Public Health 89:1369~1376
Braverman J / 2010 / How do gamblers start gambling: identifying behavioural markers for high-risk internet gambling / Eur J Public Health
Black DW / 2006 / A family study of pathological gambling / Psychiatry Res 141:295~303
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