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학술저널
저자정보
Ogura, Ichiro (Department of Oral and Maxillofacial Radiology, The Nippon Dental University School of Life Dentistry at Niigata) Kobayashi, Eizaburo (Department of Oral and Maxillofacial Surgery, The Nippon Dental University School of Life Dentistry at Niigata) Nakahara, Ken (Advanced Research Center, The Nippon Dental University School of Life Dentistry at Niigata) Haga-Tsujimura, Maiko (Department of Histology, The Nippon Dental University School of Life Dentistry at Niigata) Igarashi, Kensuke (Department of Life Science Dentistry, The Nippon Dental University) Katsumata, Akitoshi (Department of Oral Radiology, Asahi University School of Dentistry)
저널정보
대한영상치의학회 Imaging science in dentistry Imaging science in dentistry 제49권 제4호
발행연도
2019.1
수록면
281 - 286 (6page)

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Purpose: The purpose of this study was to evaluate the morphology of the mandibular cortex in cases of medication-related osteonecrosis of the jaw (MRONJ) in patients with osteoporosis or bone metastases using a computer programme. Materials and Methods: Fifty-four patients with MRONJ (35 with osteoporosis and 19 with bone metastases) were examined using panoramic radiography. The morphology of the mandibular cortex was evaluated using a computer programme that scanned the mandibular inferior cortex and automatically assessed the mandibular cortical index (MCI) according to the thickness and roughness of the mandibular cortex, as follows: normal (class 1), mildly to moderately eroded (class 2), or severely eroded (class 3). The MCI classifications of MRONJ patients with osteoporosis or bone metastases were evaluated with the Pearson chi-square test. In these analyses, a 5% significance level was used. Results: The MCI of MRONJ patients with osteoporosis(class 1: 6, class 2: 15, class 3: 14) tended to be higher than that of patients with bone metastases(class 1: 14, class 2: 5, class 3: 0)(P=0.000). Conclusion: The use of a computer programme to assess mandibular cortex morphology may be an effective technique for the objective and quantitative evaluation of the MCI in MRONJ patients with osteoporosis or bone metastases.

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