지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
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Various nanomaterials may flow into the aquatic ecosystem via production, use, and treatment processes. Especially, gold nanoparticles (AuNPs) were categorized as manufactured nanomaterials presented by the Organization for Economic Cooperation and Development Working Party on Manufactured Nanomaterials (OECD WPMN) in 2010. AuNPs have been used in medical area, however, they were reported to induce cytotoxicity and oxidative DNA damage, as well as down-regulation of the DNA repair gene in mice and human cell lines. In this study, the aquatic toxicity data of AuNPs and gold ions were collected, with the specific test methods analyzed with respect to the form and size of AuNPs, test species, exposure duration, and endpoints. Currently, aquatic toxicity data of AuNPs and gold ions have been presented in 14 studies including 4 fish, 6 crustacean, 2 green algae, and 2 macrophytes studies, as well as a further 8 studies including 4 fish, 4 crustacean, 1 platyhelminthes, and 1 green algae, respectively. The AuNPs were 0.8-100 nm in size, as gold nanoparticles, gold nanorod, glycodendrimer-coated gold nanoparticles, and amine-coated gold nanoparticles. The tested endpoints were the individual toxicities, such as mortality, malformation, reproduction inhibition, growth inhibition and genetic toxicity such as oxidative stress, gene expression, and reactive oxygen species formation. The accumulation of AuNPs was also confirmed in the various receptor organs. These results are expected to be useful in understanding the aquatic toxicity of AuNPs and gold ions, as well as being applicable to future toxicity studies on AuNPs.
목차
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참고문헌 (40)
참고문헌 신청
이우미 / 2010 / 수환경에서 나노입자의 생태독성 연구동향 / 한국물환경학회지 26(4):566~573
Bar-llan, O. / 2009 / Toxicity Assessments Of Multisized Gold And Silver Nanoparicles In Zebrafish Embryos / Small 17(5):1897~1910
Bermudez, E. / 2004 / Pulmonary Responses Of Mice, Rats, And Hamsters To Subchronic Inhalation Of Ultrafine Titanium Dioxide Particles / Toxicological Sciences 77(2):347~357
Biesinger, K. E. / 1972 / Effects Of Various Metals On Survival, Growth, Reproduction And Metabolism Of Daphnia magna / Journal of the Fisheries Research Board of Canada 29(12):1691~1700
Borgmann, U. Y. / 2005 / Toxicity Of Sixty-Three Metals And Metalloids To Hyalella azteca At Two Levels Of Water Hardness / Environmental Toxicology and Chemistry 24(3):641~652
Bar-llan, O. / 2009 / Toxicity Assessments Of Multisized Gold And Silver Nanoparicles In Zebrafish Embryos / Small 17(5):1897~1910
Bermudez, E. / 2004 / Pulmonary Responses Of Mice, Rats, And Hamsters To Subchronic Inhalation Of Ultrafine Titanium Dioxide Particles / Toxicological Sciences 77(2):347~357
Biesinger, K. E. / 1972 / Effects Of Various Metals On Survival, Growth, Reproduction And Metabolism Of Daphnia magna / Journal of the Fisheries Research Board of Canada 29(12):1691~1700
Borgmann, U. Y. / 2005 / Toxicity Of Sixty-Three Metals And Metalloids To Hyalella azteca At Two Levels Of Water Hardness / Environmental Toxicology and Chemistry 24(3):641~652
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