지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Acinetobacter baumannii is gram-negative bacilli that can be widely found in environments. Recently, A. baumannii emerged as a serious nosocomial infection. A total of 92 A. baumannii were isolated from hospitalized patients in Seoul, Korea, between December 2010 and April 2011. Antimicrobial susceptibility testing was investigated using CLSI agar dilution methods. Tigecycline non-susceptible A. baumannii isolates were investigated by repetitive extragenic palindromic sequence-based PCR (rep-PCR). Pulsed-field gel electrophoresis was performed to determine the epidemiological relationships. All clinical isolates showed high-level resistance to the most commonly used antibiotics: Ciprofloxacin (87.0%), Ampicillin/sulbactam (82.6%), Cefotaxime (81.5%), Ceftazidime (80.4%). Moreover, 50.0% of these isolates were non-susceptible to tigecycline. When evaluated by RAPD analysis, generated distinct band ranging in size from 1kb to 8k band varying from 4 to 10 bands. Stricter surveillance and more rapid detection are essential to prevent the spread of multi drug resistant A. baumannii.
목차
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참고문헌 (16)
참고문헌 신청
Bergogne-Berein, E / 1996 / Acinetobacter spp. as nosocomial pathogens: microbiological, clinical, and epidemiological features / Clin. Microbiol. Rev 9:148
Corbella, X / 2000 / emergence and rapid spread of carbapenem resistance during a large and sustained hospital outbreak of multi resistant Acinetobacter baumannii / J. Clin. Microbiol 38:4086
Giamarellou, H / 2008 / Acinetobacter baumannii: a universal threat to public health? / Int. J. Antimicrob. Agents 32:106
Seok Hoon Jeong / 2006 / Outbreaks of Imipenem-Resistant Acinetobacter baumannii Producing Carbapenemases in Korea / The Journal of Microbiology 44(4):423~431
Karageorgopoulos, D. E / 2008 / Tigecycline for the treatment of multidrugresistant (including carbapenem-resistant) acinetobacter infections: a review of the sdientific evidence / J. Antimicrob. Chemother 62:45
Corbella, X / 2000 / emergence and rapid spread of carbapenem resistance during a large and sustained hospital outbreak of multi resistant Acinetobacter baumannii / J. Clin. Microbiol 38:4086
Giamarellou, H / 2008 / Acinetobacter baumannii: a universal threat to public health? / Int. J. Antimicrob. Agents 32:106
Seok Hoon Jeong / 2006 / Outbreaks of Imipenem-Resistant Acinetobacter baumannii Producing Carbapenemases in Korea / The Journal of Microbiology 44(4):423~431
Karageorgopoulos, D. E / 2008 / Tigecycline for the treatment of multidrugresistant (including carbapenem-resistant) acinetobacter infections: a review of the sdientific evidence / J. Antimicrob. Chemother 62:45
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