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The Effect of Taping Therapy on the Expression of cFos Protein and Pain Suppression in Acute Ankle Sprain in Rats
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흰쥐의 급성 발목삠에서 테이핑요법이 cFos 단백의 발현과 통증억제에 미치는 영향

논문 기본 정보

Type
Academic journal
Author
Choi, Suck-Jun (원광보건대학교 의무부사관과) Byun, Sin-Kyu (원광보건대학교 전투부사관과) Lee, Gyoung-Wan (원광보건대학교 간호학과) Kim, Jae-Hyo (원광대학교 한의과대학 경혈학교실) Yang, Seung-Bum (원광보건대학교 의무부사관과)
Journal
경락경혈학회 Korean Journal of Acupuncture Korean journal of acupuncture 제34권 제1호 KCI Accredited Journals
Published
2017.1
Pages
1 - 7 (7page)

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The Effect of Taping Therapy on the Expression of cFos Protein and Pain Suppression in Acute Ankle Sprain in Rats
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Objectives : The purpose of this study was to evaluate effects of taping therapy on recovery of behavioral symptoms and neural excitability of the lumbar spinal cord in rat model for ankle sprain. Methods : Adult Sprague-Dawley rats was used and divided into 3 experimental groups: normal group(n=6), ankle sprain(n=6), and ankle sprain with taping treatment(n=6). In order to induce ankle sprain the right ankle joint was injured with 4~5 repetitive over-flexions and over-extensions manually. The severity of joint pain was evaluated by measuring foot weight bearing force ratio(FWBRF) of the hind limb and the injury-induced edema formation by diameter of the joint following ankle sprain. The changes of neural excitability in the lumbar spinal cord was tested by observation of cFos protein expression, a metabolic marker for neural excitation. Results : Severity of ankle injury induced in this experiment coincided with Grade 1 ankle sprain. Compared with ankle sprain group, ankle sprain＋taping showed a significant reductions of joint pain as well as of edema formation at the ankle joint following ankle sprain. There was significant upregulation of cFos-immunoreactive neurons in the lumbar spinal cord 24 hours after ankle sprain. In contrast, taping therapy resulted in significant inhibition of cFos-immunoreactive neurons in the lumbar spinal cord. Conclusions : Collectively, these results suggest that taping therapy may be an alternative therapeutic intervention for symptom recovery of the mild ankle sprain.
#ankle sprain #taping therapy #foot weight bearing force ratio #cFos-immunoreactive neurons

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References (26)

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Han KJ / 2004 / Clinical Research on Effect Technique of Auricular Acupuncture Therapy on Ankle sprain / Daejeon University Institute of Oriental Medicine’s collection of dissertations 13(1):287~293 google schola Kim EK / 2014 / Surveillance of Sports Injury and Illness at the Sports Medicine Clinic of Korea National Sport University during 2013 / Sports Science 31(2):77~83 google schola Wolfe MW / 2001 / Management of ankle sprains / Am Fam Physician 63(1):93~104 google schola Hanuri Editorial Department. / 2002 / The Merck Manual / Hanuri publishing :526~527 google schola Anandacoomarasamy A / 2005 / Long term outcomes of inversion ankle injuries / Br J Sports Med 39:14 google schola

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