지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 29 - 35 (7page)
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초록· 키워드
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Objectives : To provide the information of preservation method for herbal decoction, we evaluated the anti-inflammatory effects according to preservation temperature and period of Pyungwi-san (PWS, Ping wei-san) decoction. Methods : The anti-inflammatory activity of PWS was investigated by carrageenin-induced paw edema in SD rats. At 0 month, PWS extract was administrated 100, 300 and 1000 mg/kg/day orally for seven days prior to induction of edema. Edema was induced by subcutaneous injection of 1% carrageenin into the right hind paw. The paw volume was measured at 4 hr following carrageenin-induced paw edema in rats. At 6 and 12 months, PWS extracts according to preservation temperatures (room temperature, $4^{\circ}C$ and $-20^{\circ}C$) were administrated in rats and then carrageenin-induced paw edema volume was measured. Results : PWS showed inhibitory effect on carrageenin-induced paw edema in rats and the optimal dose was 1000 mg/kg/day at 0 month of storage. At 6 month of storage, PWS storaged at $4^{\circ}C$ and $-20^{\circ}C$ were inhibited paw edema but that storaged at room temperature was not reduced paw edema in rats. Conclusions : These results suggest that PWS decoction pouch has anti-inflammatory activities at both $4^{\circ}C$ and $-20^{\circ}C$ during 6 month storage.
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참고문헌 (18)
참고문헌 신청
김호철 / 한의신문
식품의약품안전청 / 2012 / 의약품등의안정성시험기준 / 고시 제2012-54호
한의과대학 방제학 교수 / 1999 / 방제학 / 영림사 :486
Park SH / 2000 / A study on the effects of Pyungwee-san and compounding of medicine in Pyungwee-san on the movement of gastrointestinal smooth muscles, anticatharsis and central nervous system / J. Oriental Chr. Dis. 6(1):184~196
Shin CH / 1990 / Const, In Effects of Pyeong yoe san extract and Jo gi pyeong yoe san extract on the experimental gastric ulcer in rats / J. Const. Med. 2(1):189~197
식품의약품안전청 / 2012 / 의약품등의안정성시험기준 / 고시 제2012-54호
한의과대학 방제학 교수 / 1999 / 방제학 / 영림사 :486
Park SH / 2000 / A study on the effects of Pyungwee-san and compounding of medicine in Pyungwee-san on the movement of gastrointestinal smooth muscles, anticatharsis and central nervous system / J. Oriental Chr. Dis. 6(1):184~196
Shin CH / 1990 / Const, In Effects of Pyeong yoe san extract and Jo gi pyeong yoe san extract on the experimental gastric ulcer in rats / J. Const. Med. 2(1):189~197
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